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Consider mass transfer from pulmonary capillaries to a single alveolus

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Consider mass transfer from pulmonary capillaries to a single alveolus. Suppose that, in addition to the normal 0.6 μm thick tissue layer between the blood and the air, scar tissue has formed that is 1μm thick. The effective diffusivity of CO2 in this scar tissue is 0.7 × 10−6 cm2/s. When CO2 has to cross both the “normal” tissue and the scar tissue, the mass transfer efficiency of the alveolus is reduced. Considering the entire alveolus, compute the net percentage reduction in blood-to-air CO2 transfer due to the scar tissue for a 50 μm long capillary. Note: you do not need to re-derive equations; you should be able to make some simple modifications to equations in the text to get what you need. Remember that when two mass transfer barriers are in series, their mass transfer resistances add. You may use parameter values (except for capillary length) given in Section 7.4.1.

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