Lower Columbia College

Microbiology 260

1)How many people are infected with untreatable (drug-resistant) bacterial infections each year? How many people die? 2 million people are infected with drug-resistant superbugs each year. 23 thousand die

2. What type of resistant bacterial infections did 11.5 year-old Addie Rerecich suffer from? Did Addie survive? (note: whether she lives or dies is a follow-up later in the film.)

3. What does pandrug-resistant mean?

4. Summarize what happened to David Ricci in Calcutta, India – how did he get hurt? How did doctors at the hospital in India treat David? Did David survive? (note: whether he lives or dies is a follow-up later in the film.)

5. What does NDM-1 stand for? This gene exists in at least 11 types of bacteria in India. Where are these bacteria found?

6. What is colistin therapy? What are the inherent problems with colistin therapy?

7. What Gram reaction is Stenotrophomonas maltophilia? Where is this organism usually found? (hint: needs internet research)

8. A prestigious hospital worked hard to combat a KPC outbreak in the summer of 2011. What hospital? How was the KPC outbreak spreading within the hospital?

9. What does KPC stand for? What gram reaction is KPC? Where is this organism usually found? (hint: needs internet research).

10. Why have drug companies that used to develop and manufacture antibiotics stopped putting capital into antibiotic development? Because the more you expose bacteria to an antibiotic, the more that

11. Where are most antibiotics in the United States used? What are the advantages to this antibiotic use?

12. Lance Price (T-Gen Research Institute) and team was investigating E. coli urinary tract infections (UTI’s) in the Flagstaff hospital. What was the hypothesis they were testing? How was the study conducted? What were the results?