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Homework answers / question archive / University of Illinois, Chicago NURS 531 Chapter 49: Drug addiction, dependence, and abuse MULTIPLE CHOICE 1)All dependence-producing drugs act via different pathways to cause   depletion of norepinephrine in the locus coeruleus depletion of dopamine in nigrostriatal pathways depletion of glutamate in meso-limbic pathways   the release of glutamate in the frontal cortex the release of dopamine in the nucleus accumbens     2

University of Illinois, Chicago NURS 531 Chapter 49: Drug addiction, dependence, and abuse MULTIPLE CHOICE 1)All dependence-producing drugs act via different pathways to cause   depletion of norepinephrine in the locus coeruleus depletion of dopamine in nigrostriatal pathways depletion of glutamate in meso-limbic pathways   the release of glutamate in the frontal cortex the release of dopamine in the nucleus accumbens     2

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University of Illinois, Chicago

NURS 531

Chapter 49: Drug addiction, dependence, and abuse

MULTIPLE CHOICE

1)All dependence-producing drugs act via different pathways to cause

 

  1. depletion of norepinephrine in the locus coeruleus
  2. depletion of dopamine in nigrostriatal pathways
  3. depletion of glutamate in meso-limbic pathways

 

  1. the release of glutamate in the frontal cortex
  2. the release of dopamine in the nucleus accumbens

 

 

2.    Chronic administration of morphine is believed to cause tolerance by

 

  1. increasing expression of adenylate cyclase
  2. decreasing expression of adenylate cyclase
  3. increasing expression of guanylate cyclase
  4. decreasing expression of guanylate cyclase
  5. increasing expression of a-adrenoceptors

 

 

3.    Nicotine use often leads to drug dependence by activation of nicotinic receptors in the

 

  1. nucleus accumbens
  2. hippocampus
  3. ventral tegmental area
  4. cerebral cortex
  5. striatum

 

 

4.    Disulfiram has been used to facilitate abstinence from ethanol based on its ability to inhibit

 

  1. the mesolimbic dopaminergic pathway
  2. ethanol withdrawal symptoms
  3. alcohol dehydrogenase
  4. aldehyde dehydrogenase
  5. aldehyde oxidase

 

 

5.    The effects that result from smoking marijuana include

 

  1. improved motor coordination
  2. improved memory
  3. increased creativity
  4. loss of appetite
  5. conjunctival vasodilatation

 

 

6.    Which drug is used in the treatment of drug dependence because of its ability to reduce withdrawal symptoms?

 

  1. clonidine
  2. methadone
  3. bupropion
  4. naltrexone
  5. acamprosate

7.    The fetal alcohol syndrome is associated with malformations that typically include

 

  1. increased cranial circumference
  2. abnormal limb development
  3. abnormal facial development
  4. neural tube birth defects
  5. cleft palate

 

 

8.    A sustained-release formulation of bupropion is used to facilitate abstinence in persons who are addicted to

 

  1. ethanol
  2. cocaine
  3. nicotine
  4. heroin
  5. marijuana

 

 

9.    Metabolism of the amount of ethanol contained in substantial quantities of alcoholic beverages may lead to a depletion of

 

  1. essential amino acids
  2. acetaldehyde
  3. reduced nicotinamide adenine dinucleotide (NADH)
  4. nicotinamide adenine dinucleotide (NAD+)
  5. lactate

 

 

10.  Moderate ingestion of ethanol reduces mortality associated with

 

  1. lung cancer
  2. liver disease
  3. coronary heart disease
  4. hypertension
  5. renal disease

 

 

11.  In this decade, the incidence of cigarette smoking is

 

  1. increasing in developing countries
  2. decreasing in developing countries
  3. increasing in the UK but decreasing in developing countries
  4. decreasing in the UK but increasing in developing countries
  5. increasing in all countries studied

 

 

12.   Ingestion of ethanol typically increases the secretion of

 

  1. testosterone
  2. antidiuretic hormone
  3. adrenocorticotrophic hormone
  4. growth hormone
  5. glucagon

 

 

 

 

 

 

 

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