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Annabeth and Percy are concerned about having a child with Canavan disease, which causes brain tissue degeneration

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Annabeth and Percy are concerned about having a child with Canavan disease, which causes brain tissue degeneration. This condition, which is very rare, has affected Annebeth's uncle (her mother's brother) and Percy's sister. No one else in either family has the condition.

a) What is the most likely mode of inheritance of Canavan disease? 

b)Based on their family history, what is the probability Annabeth and Percy's first child will be affected by Canavan disease?

c)What is the probability their first child will be a carrier?

d)What is the probability their first child will be affected by both diseases?