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University of Tennessee BIOL 240 Chapter 6: 1)What is meant by gene interactions? What are some of those interactions? 2

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University of Tennessee

BIOL 240

Chapter 6:

1)What is meant by gene interactions? What are some of those interactions?

2.            What is complete dominance? What is haploinsufficient?

3.            What are gain-of-function and loss-of-function mutations? Know each of the different types: amorphic, hypomorphic, hypermorphic, dominant negative.

4.            What is incomplete dominance? What about codominance? Are they the same thing? What are some examples?

5.            What are the alleles for the ABO blood group? What are the genotypes for each blood type?

6.            Does one gene always lead to the characteristics of one trait? Can there be more than one variation of a gene? Can one trait be affected by more than one gene?

7.            What is pleiotropy?

8.            What is a lethal allele? Is there a difference between recessive and dominant lethals? Name some examples.

9. What is lethal load?

 

10.          What are conditional mutants? Name some examples.

 

11.          What are sex-limited traits? How is that different from sex-influenced traits?

12.          What is penetrance? What is incomplete penetrance? What is variable expressivity?

13.          What are the three types of genetic pathways?

14.          What is the one-gene-one-enzyme hypothesis?

 

 

15.          Whatis epistasis?Whatis recessiveepistasis?Whatis theexpectedratioof this incidence?Whatis dominantepistasis?Whatis theexpectedratioin thiscase?

 

 

 

 

 

16.          Whatis dominantsuppression?Whatis theexpectedratio?

 

17.          Whatarecomplementationtests?

18.          Reviewphenotypicratiosonslide79,Table6-2.

 

19.          Is phenotypealwaysa directreflectionof genotype?If not,whatelsecomesin toplay?

 

 

20.          Whatis variablepenetranceandvariableexpressivity?

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