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A scientist is investigating some colon cancer cells. He notices that the cells have a high activity of the enzyme MAP kinase kinase. Which of the following is (are) likely explanations for this? A) The cell has a mutant growth factor receptor that is always active. B) The cell has a mutant adenylyl cyclase that is always active. C) The cell has a mutant Ras that cannot hydrolyze GTP. D) The cell has a mutant MAP kinase that is always active. E) The cell has a mutant tumor suppressor gene that cannot block expression of genes that stimulate cell division.