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1)Discuss the subcellular localization and signaling mechanisms of the CB1 receptor

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1)Discuss the subcellular localization and signaling mechanisms of the CB1 receptor.

2)Describe the features of cannabinoid receptor pharmacology presented in the text. Your answer should include a description of both receptor agonists (natural versus synthetic, full versus partial agonism) and receptor antagonists.

3)Discuss the functional roles of CB1 and CB2 receptors as revealed by pharmacological and genetic approaches.