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Homework answers / question archive / For this exercise, let's assume that you are setting up this study, rather than being called in after the fact
For this exercise, let's assume that you are setting up this study, rather than being called in after the fact. A review of the clinic's records indicates that their 8-week diet produces an average weight loss of 3.1 kg, with a standard deviation of ? 2.4 kg. If we desire to measure a large effect (Cohen's d ? 0.8), then the mean difference between groups (our desired effect size) should be at least:
0.8 x 2.4 = 1.92 kg
QUESTIONS TO ANSWER
? Description of data analysis procedures (one paragraph)
? Selection/justification of your basic statistical approach
? Any modification made based on your test(s) of assumptions
? Description of findings (paragraph or two)
? Summary table comparing groups
? Accompanying narrative statement on CI of differences and t-test
? Description of effect size and power of the analysis
? Compute the Number of Subjects Needed to Achieve a Given Power and Effect
The same text is in the attached file.
QUESTIONS TO ANSWER
? Description of data analysis procedures (one paragraph)
o Selection/justification of your basic statistical approach
o Test(s) of assumptions underlying the statistical approach
o Any modification made based on your test(s) of assumptions
I would do a 2-sample t-test without equal variances assumed (you could do it with equal variances assumed, it probably wouldn't make a difference because the standard deviations of the groups are pretty similar). The test statistic is calculated as:
So, in this situation, t = (-1.1111 - (-5.0111)) = 3.9/√2.567 = 7.697
√(1.89888/18 + 2.72178/18)
This value for t is significant at the 0.001 level (2-tailed probability; compare to a t-distribution with 34 degrees of freedom). Therefore you can reject the null hypothesis that the means of group 1 and group 2 are equal, and assume the alternative hypothesis that they are different.
This test assumes that the two groups are normally distributed. This was shown with the Q-Q plots (the plots are linear) and with the Kolmogorov-Smirnov and Shapiro-Wilk tests (the p-values are large, so the null hypothesis of normality can not be rejected). Therefore, there are no modifications that need to be made.
? Description of findings (paragraph or two)
o Summary table comparing groups
o Accompanying narrative statement on CI of differences and t-test
o Description of effect size and power of the analysis
The summary tables are below (the simplest way to summarize the data is with the box-and-whisker plot). Group 1 has a larger mean (less weight loss?) and a smaller variance than group 2.
T-test: As was shown in the t-test above, the two groups have statistically significantly different means.
Confidence interval: To calculate the 95% confidence interval for the difference of the means, we use the following formula:
-1.1111 - (-5.0111)) ± (2.032)(2.3468)(.3333)
3.9 ± 1.588
(2.312, 5.488)
(the t-value of 2.032 comes from the 95% critical value for a t-distribution with 34 degrees of freedom)
Effect size: The desired effect was 1.92, and, as the entire 95% confidence interval is greater than 1.92, you can be confident that the actual difference between the group means is larger than 1.92 kg.
Power: At the top of the page, the power was calculated as 0.9979. The power equals 1 - β, where β is the Type II error rate ("false negative" error, i.e. the alternative hypothesis is actually true, but you do not reject the null hypothesis). Here, 0.9979 = 1 - β, so β = 0.0021. That means that there is a 0.21% type II error rate.