Homework answers / question archive / University of South Alabama NU 545 Chapter 28 Quiz : Alterations of Hematologic Function in Children 1)Which of the following is TRUE regarding fetal and adult Hgb? The adults Hgbs are HbA and HbA2 and they are composed of two a chains and two B chains Fetal Hgb is HbF Embryonic hemoglobin’s are Gower 1, 2, 3   Which of the following is TRUE regarding anemia in children? The most common cause is iron deficiency There are two causes for hemolytic anemia: increases destruction and disorders r/t damaging extraerythrocytic factors   Which of the following is TRUE regarding iron deficiency anemia?   Which of the following is TRUE regarding iron deficiency? Splenomegaly is evident in 10-15% of children with iron deficiency anemia If condition is long standing, the sutures of skull may widen   Which of the following is TRUE regarding maternal antibodies? Placental detachment results in large number of fetal erythrocytes entering mothers bloodstream The first- Rh incompatible pregnancy usually presents no difficulty Anti-Rh antibodies are formed in the response to the presence of incompatible (Rh- positive) erythrocytes in the blood of an Rh-negative mother   Which of the following is the appropriate term for an alloimmune disease in which maternal blood and fetal blood are antigenically incompatible? Hydrops fetalis→term for fetuses that do not survive anemia in utero→stillborn with gross edema to entire body Icterus neonatorum→neonatal jaundice   Which of the following is TRUE regarding the Coombs test? Indirect Coombs measures antibody in the mother circulation and indicates if the fetus is at risk for hemolytic disease Direct Coombs test measures antibody already bound to the surfaces of fetal erythrocytes and is used primarily to confirm dx of antibody-mediated hemolytic disease   Which of the following is TRUE regarding G6PD deficiency? G6PD is most commonly found in males It results in hemolysis and fava beans and the ingestion of certain drugs can cause a reaction   Which of the following is associated with hereditary spherocytosis? It is autosomal dominant Heinz bodies are found in G6PD   Which of the following describes a person with Hb(s) and another type of abnormal Hgb? Sickle cell anemia has two Hb(s) genes Sickle cell trait has one Hb(s) and one normal Hg(A) Hereditary spherocytosis often represents new mutation   Which of the following is a TRUE statement regarding sickle cell disease?   Which of the following is the most common trigger for sickling?       Which of the following is the appropriate term for transient cessation in red blood cell production resulting in acute anemia? Vaso-occlusive crisis: when cells clump and occlude vessels→may develop spontaneously or be precipitated by infection, cold temp, dehydration, or low pH Sequestration crisis→large amounts of blood become pooled in the liver and spleen   Which of the following hemophilias is autosomal recessive and is found equally in males and females? Hemophilia A and B are X-linked recessive and found in med Von Willebrand disease is autosomal dominant  

University of South Alabama NU 545 Chapter 28 Quiz : Alterations of Hematologic Function in Children 1)Which of the following is TRUE regarding fetal and adult Hgb? The adults Hgbs are HbA and HbA2 and they are composed of two a chains and two B chains Fetal Hgb is HbF Embryonic hemoglobin’s are Gower 1, 2, 3   Which of the following is TRUE regarding anemia in children? The most common cause is iron deficiency There are two causes for hemolytic anemia: increases destruction and disorders r/t damaging extraerythrocytic factors   Which of the following is TRUE regarding iron deficiency anemia?   Which of the following is TRUE regarding iron deficiency? Splenomegaly is evident in 10-15% of children with iron deficiency anemia If condition is long standing, the sutures of skull may widen   Which of the following is TRUE regarding maternal antibodies? Placental detachment results in large number of fetal erythrocytes entering mothers bloodstream The first- Rh incompatible pregnancy usually presents no difficulty Anti-Rh antibodies are formed in the response to the presence of incompatible (Rh- positive) erythrocytes in the blood of an Rh-negative mother   Which of the following is the appropriate term for an alloimmune disease in which maternal blood and fetal blood are antigenically incompatible? Hydrops fetalis→term for fetuses that do not survive anemia in utero→stillborn with gross edema to entire body Icterus neonatorum→neonatal jaundice   Which of the following is TRUE regarding the Coombs test? Indirect Coombs measures antibody in the mother circulation and indicates if the fetus is at risk for hemolytic disease Direct Coombs test measures antibody already bound to the surfaces of fetal erythrocytes and is used primarily to confirm dx of antibody-mediated hemolytic disease   Which of the following is TRUE regarding G6PD deficiency? G6PD is most commonly found in males It results in hemolysis and fava beans and the ingestion of certain drugs can cause a reaction   Which of the following is associated with hereditary spherocytosis? It is autosomal dominant Heinz bodies are found in G6PD   Which of the following describes a person with Hb(s) and another type of abnormal Hgb? Sickle cell anemia has two Hb(s) genes Sickle cell trait has one Hb(s) and one normal Hg(A) Hereditary spherocytosis often represents new mutation   Which of the following is a TRUE statement regarding sickle cell disease?   Which of the following is the most common trigger for sickling?       Which of the following is the appropriate term for transient cessation in red blood cell production resulting in acute anemia? Vaso-occlusive crisis: when cells clump and occlude vessels→may develop spontaneously or be precipitated by infection, cold temp, dehydration, or low pH Sequestration crisis→large amounts of blood become pooled in the liver and spleen   Which of the following hemophilias is autosomal recessive and is found equally in males and females? Hemophilia A and B are X-linked recessive and found in med Von Willebrand disease is autosomal dominant  

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9. Which of the following is associated with hereditary spherocytosis?
   • It is autosomal dominant
   • Heinz bodies are found in G6PD

 

10. Which of the following describes a person with Hb(s) and another type of abnormal Hgb?
    • Sickle cell anemia has two Hb(s) genes
    • Sickle cell trait has one Hb(s) and one normal Hg(A)
    • Hereditary spherocytosis often represents new mutation

 

11. Which of the following is a TRUE statement regarding sickle cell disease?

 

12. Which of the following is the most common trigger for sickling?

 

 

 

13. Which of the following is the appropriate term for transient cessation in red blood cell production resulting in acute anemia?
    • Vaso-occlusive crisis: when cells clump and occlude vessels→may develop spontaneously or be precipitated by infection, cold temp, dehydration, or low pH
    • Sequestration crisis→large amounts of blood become pooled in the liver and spleen

 

14. Which of the following hemophilias is autosomal recessive and is found equally in males and females?
    • Hemophilia A and B are X-linked recessive and found in med
    • Von Willebrand disease is autosomal dominant