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Georgia State University BIOL 2300 1)Which Ig can cross the placenta 2

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Georgia State University

BIOL 2300

1)Which Ig can cross the placenta

2. Which Ig is in the body fluids and mucosal layers ? that can also be passed to babies via breast feeding?

 

 

3. Which Ig accounts the most for anaphylactic allergic reactions ?

 

 

4. Which Ig is produced first during a primary exposure to a pathogen?

 

 

5. Which Ig is the most predominant in the human body?

 

 

6. A term synonymous with antibody is

a.            antigen.

b.            epitope.

c.             determinant.

d.            immunoglobulin.

 

. 7. Which of the following antibodies is a pentamer?

a.            IgA

b.            IgD c. IgM

d. IgE

8. Which of the following antibodies is a dimer? a. IgA

b.            IgD

c.             IgM

d.            Ig

9. The immunoglobulin monomer consists of

a.            4 large chains.

b.            2 heavy and 2 light chains.

c.             5 light chains.

d.            3 heavy and 3 light chains

10. Which class of antibody accounts for the bulk of the circulating antibody?

a.            IgA

b.            IgD c. IgG

d. IgE

 

11. An IgG molecule has two

a.            heavy chains.

b.            light chains.

c.             antibody binding sites.

d.            antigen binding sites. e. a, b and d

 

12. Antigens interact with antibodies at

a.            the outer end of each arm of the Y.

b.            the junction of heavy and light chains.

c.             different regions depending on the class of antibody.

d.            the bottom stem of the heavy chain of the Y.

 

 

13. The only class of antibody that can cross the placenta is

a.            IgA.

b.            IgD. c. IgG.

d. IgE.

 

14. Which is the first antibody class made during the primary response to an antigen?

a. IgA b. IgM

c. IgG

d. IgE

 

15. Which of the following is the most abundant immunological class produced? a. IgA

b.            IgD

c.             IgG

d.            IgE

 

16. Which of the following class of antibody is primarily found in external secretions? a. IgA

b.            IgD

c.             IgG

d.            IgE

17. The immunoglobulin that is important in hypersensitivity (allergic) reactions is

a.            IgA.

b.            IgD.

c.             IgG. d. IgE.

 

 

Matching

 

55.          IgG (b)  a. found on the surface of B cells

56.          IgM (e) b. agglutinates antigens

57.          IgA (c)   c. protects mucous membranes

58.          IgE (d)   d. involved in hypersensitivity

59.          IgD (a)   e. first antibody produced during primary response

 

 

 

18. Factors that work generically against any foreign substance entering the host are described as

A.            innate immunity.

B.            specific immunity.

C.            irregular immunity.

D.            immune metabolism.

 

 

19. The cells primarily involved in all immune responses are the

A.            erythrocytes.

B.            platelets.

C.            osteocytes. D. leukocytes.

 

20. In humans, the stem cells from which all blood cells arise are found in the

A.            peripheral circulation.

B.            lymphatic vessels.

C.            lymph nodes. D. bone marrow.

 

21. All blood cells originate from the

A.            erythrocyte.

B.            leukocytic stem cell.

C.            eosinophilic stem cell. D. hematopoietic stem cell.

 

22. Which of the following is a phagocytic cell found in the human body?

A. erythrocyte B. neutrophil

C. B cell

D. T cell

 

23. The leukocyte that contains histamine is the

A.            lymphocyte.

B.            monocyte.

C.            macrophage. D. basophil.

 

24. The cytokine produced by host cells in response to viral infections like cold viruses is A-          complement.

B-            lysozyme.

C-            histamine. D-     interferon.

 

 

 

 

 

25. Which of the following is not a granulocyte?

a. eosinophil b. macrophage

 

c. basophil

d. mast cell Complement

 

26. The cytokine produced by host cells in response to viral infections like cold viruses is A-          complement.

B-            lysozyme.

C-            histamine. D-     Interferon

 

27. Which of the following is NOT considered as innate immunity: A-       Inflammation

B-            Phagocytosis

C-            Interferon release

D-           Cell mediate response E-              Fever

 

28. During phagocytosis pathogen is killed in the following cell organelle A-          Phagosome

B-            Lysosome

C-            Phagolysosome D-          Mitochondria

E-            E- endoplasmic reticulum

 

 

29. Which complement protein/(s) is act as chemoattractant/(s) at the beginning of inflammation process

A-           C3b-C5b

B-            C3a C3b

C-            C5a C5b

D-           C3a C5a E-           C3a C5a

 

 

 

30. The Cytokines produced by mast cells and basophils for chemotaxis A-           Interleukin IL2

B-            CSF.

C-            histamine. D-     interferon.

 

31. The immune response that has a memory response following first exposure to specific pathogen:

A – Inflammation A-       Interferon

B-            Fever

C-            Addaptive response D- Innate response

 

32. The immune cells that play a role in both innate and adaptive immunity A-    Basophils

B-            Neutrophils C-   Macrophages D-               Mast cells

 

33. -The defense system utilizing highly specialized cells and chemicals that develop in response to specific organisms and foreign materials is the

a.            generalized defense system.

b.            innate immune system. c. adaptive immune system.

d. autoimmunity.

 

 

 

34. Adaptive immunity is slow during primary exposure but very fast during consecutive exposures

A-           True B- False

 

35. Inflammation always occur during a disease A-            True

B-            False

 

 

36. Which of the following are referred to as mononuclear phagocytes?

A.            lymphocytes and basophils

B.            mast cells and eosinophils

 

C.            basophils and eosinophils

D.            monocytes and macrophages

 

37. The leukocyte responsible for adaptive immunity is the A. lymphocyte.

B.            monocyte.

C.            eosinophil.

D.            neutrophil.

 

 

38. Cell adhesion molecule play an important role during A-         Direct cell to cell contact

B-            Fever

C-            Interferon release

D-           Inflammation

E-            E A and D

 

39. A group of interacting serum(blood) proteins that provide a nonspecific defense mechanism is

A.            complement.

B.            interferon.

C.            glycoprotein.

D.            lysozyme.

 

 

40. Interleukins are proteins A. produced by leukocytes.

B. important in both innate and adaptive immunity. D. protein molecules.

E. A and B

 

41. Interferons function to make cells A. resistant to viral replication.

B.            lyse when exposed to virus.

C.            non-motile when infected with virus.

D.            resistant to phagocytosis.

 

42. The cellular organelle responsible for the digestion of ingested infectious agents is the

A.            endoplasmic reticulum.

B.            Golgi apparatus. C. phagolysosome.

D. lysosome.

 

43. Following digestion of a microorganism by phagocytes, the debris is excreted by

A.            ingestion.

B.            exocytosis.

C.            extrusion.

D.            budding.

 

44. The four cardinal signs of inflammation are:

A.            flare, wheals, fever, cough

B.            rash, pus, heat, rubor

C.            heat, pain, vesicles, fever

D.            redness, heat, swelling, pain

 

45. the first host immune response to a nonspecific tissue injury is described as A. inflammation.

B.            reaction.

C.            antibodies.

D.            trauma.

 

46. The first kind of leukocyte lured from circulation to the site of inflammation is the A. neutrophil.

B.            monocyte.

C.            macrophage.

D.            basophil.

 

 

47. The attraction of leukocytes to the area on inflammation is referred to as

A.            parasitism.

B.            infection.

C.            phototaxis. D. chemotaxis.

 

 

48. The type of leukocyte that is found in the tissues throughout the body, is actively phagocytic, and constitutes the mononuclear phagocyte system is the

•             A-           neutrophil.

•             B-            B- basophil.

•             C-            C- eosinophil.

•             D-           D- lymphocyte

•                             E-            E- monocyte

 

49. Mast cells are only found in the blood. A True

B- False.

 

50. Lymphocytes are the cells primarily responsible for the specific adaptive immune responses.

A- True B- False