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Biology

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1.    ________ function in humoral immunity, while ________ function in cellular immunity.

Group of answer choices

 

B cells, T cells

 

B cells, mast cells

 

monocytes, basophils

 

T cells, B cells

 

basophils, T cells

 

2.    Lymphocytes that can attack foreign, tumor or virally infected cells are

Group of answer choices

 

cytotoxic T cells.

 

neutrophils.

 

plasma cells.

 

memory B cells.

 

helper T cells.

 

3.    The specificity of an antibody for its antigen is due to the:

Group of answer choices

 

the light chain.

 

the variable portions of the heavy and light chains.

 

the disulfide bridges.

 

the constant portions of the heavy and light chains.

 

the heavy chain.

 

4.    Match the antibody class with its best definition.

Group of answer choices ( IgA, IgG, IgE, IgM)

 

dimer secreted into nasal passages, tears, breast milk

                                          

80% of the human serum antibodies 

                                          

largest in size; first antibody made in primary and secondary response

                                         

involved in allergic response 

 

5.    The binding of an immunoglobulin to a microbe can result in

Group of answer choices

 

opsonization.

 

neutralization.

 

All of the other answers can result from an immunoglobulin binding a microbe.

 

agglutination.

 

complement fixation.

 

6.    The major histocompatibility complex is/are:

Group of answer choices

 

glycoproteins, called MHC receptors, found on all nucleated body cells.

 

located free-floating in the thymus gland.

 

series of genes that code for RBC receptors.

 

all of the other answers are correct

 

not recognized by the body's immune system.

 

 

7.    Helper T cells are activated by antigen presented on:

Group of answer choices

 

MHC II

 

either MHC I and MHC II

 

MHC I

 

both MHC I and MHC II presenting the same antigen

 

8.    ____________ is when antigens normally presented with MHC II are presented on MHC I for CD8 cytotoxic T cells.

Group of answer choices

 

class switching

 

clonal expansion

 

regulatory T cells

 

thymic selection

 

cross presentation

 

9.    TCRs recognize epitopes made of which type of molecule?

Group of answer choices

 

nucleic acids

 

phospholipids

 

proteins

 

carbohydrates

 

Lipopolysaccharides

 

10. ________ are proteases made by CD8 CTLs that enter pores generated by perforins to induce apoptosis.

Group of answer choices

 

cytokines

 

superantigens

 

corticosteroids

 

granzymes

 

granules

 

11. Which bacterial pathogen species can produce superantigen to trigger toxic shock syndrome?

Group of answer choices

 

Yersinia

 

Staphylococcus

 

Escherichia

 

Clostridium

 

Listeria

 

12. All about B cells is correct except:

Group of answer choices

 

All other statements about B cells are correct.

 

They mature into antibody secreting cells after encountering their specific antigens.

 

They have B cell receptors on their surfaces.

 

They form naïve mature clones after their BCR recognizes its specific free antigens.

 

They originate in the bone marrow.

 

 

13. The secondary response of humoral immunity

Group of answer choices

 

depends on the activity of memory B cells.

 

All of the other statements are true

 

results in elevated titers (levels) of antibodies sooner than in the primary response.

 

produces antibodies have higher affinity for their epitopes

 

can occur even if the second exposure occurs years after the first one.

 

14. Which is the term for plasma B cells producing different antibody monomers with the same epitope specificity?

Group of answer choices

 

cross presentation

 

clonal expansion

 

maturation

 

regulation

 

class switching

 

15. Immunity resulting from a chicken pox infection is called

Group of answer choices

 

autoimmunity.

 

artificial active immunity.

 

natural passive immunity.

 

natural active immunity.

 

artificial passive immunization.

 

16. This class of vaccine is made from a capsule polysaccharide bound to a protein.

Group of answer choices

 

conjugate

 

toxoid

 

live attenuated

 

inactivated

 

subunit

 

17. All are types of allergens except:

Group of answer choices

 

ingestants

 

contactants

 

complement

 

inhalants

 

injectants

 

18. Excessive and damaging response of the immune system against an antigen is called:

Group of answer choices

 

artificial passive immunity

 

immunology

 

hypersensitivity

 

immune tolerance

 

immunodeficiencies

 

19. All are Type I Immediate Hypersensitivity conditions except:

Group of answer choices

 

contact dermatitis

 

hives

 

peanut allergy

 

hay fever

 

allergy-induced asthma

 

20. The serum of most people with blood type B, Rh- , who have never been pregnant or received a blood transfusion, will have which immunoglobulins?

Group of answer choices

 

anti - A, anti - Rh

 

anti - A

 

anti - A, anti - B, and anti - Rh

 

anti - B, anti - Rh

 

anti - B

 

21. What is a result of desensitization allergen shots?

Group of answer choices

 

keeps the plasma cells from synthesizing IgE

 

inhibits T cells from releasing perforins and granzymes

 

increase memory cells and IgG blocking antibody levels to bind allergen

 

are monoclonal drugs that inactivate IgE

 

counteract effects of a cytokines

 

22. All are immune system responses exhibited by most people except:

Group of answer choices

 

tuberculin response if previously infected with tuberculosis

 

blood type incompatibility

 

contact dermatitis caused by jewelry

 

contact dermatitis caused by poison ivy

 

rejection of incompatible tissue graft

 

23. All are true about Type III Hypersensitivities except:

Group of answer choices

 

complement gets activated

 

chronic inflammation causes damage in tissues and organs

 

cytotoxic T cells secrete cytokines to stimulate macrophages

 

antibodies form complexes with antigens

 

immune complexes become lodged in walls of blood vessels

 

24. Type I Hypersensitivity requires sensitization and degranulation.

Group of answer choices

 

True

 

False

 

25. Hemolytic transfusion reaction Type II Hypersensitivity normally requires sensitization.

Group of answer choices

 

True

 

False

 

26. Type IV Hypersensitivity requires sensitization and subsequent exposure to allergen.

Group of answer choices

 

True

 

False

 

27.Primary immunodeficiences can be caused by malnutrition

Group of answer choices

 

True

 

False

 

28. Which disease is based on lots of autoantibodies forming immune complexes with their antigen?

Group of answer choices

 

severe combined immunodeficiency

 

anaphylactic shock

 

rheumatoid arthritis

 

asthma

 

hemolytic disease of the newborn