A quick way to verify the accuracy of your calculations is to verify that the equation below is met

A quick way to verify the accuracy of your calculations is to verify that the equation below is met. The equation simply involves that the fixation in the overall population, F IT, can be partitioned into Fis and FST. (1-FIT) = (1- FIS) * (1- FST) Use your fixation values to verify if they satisfy the partitioning of genetic fixation over the different levels of the reference world population. 4. Refer to equation of fractional heterozygous (HI / HT = (HI/ Hs) X (Hs / HT)) and transform it to demonstrate its mathematical equivalence with the equation of fixation partitioning provided in question 3.

SPSmart's homepage ENGINES USC home . SEARCH . help . software . about . contact frequencies statistics downloads Population Set 1: AFRICA (N=246), EUROPE (N=380), EAST ASIA (N=286), AMERICA (N=181) SNP chr pos gene ref anc var population N MA MAF HOBS HEXP FS FST In rs12913832 15 28365618 HERC2 A A AG Population Set 1 1093 G 0.291 0.188 0.413 - 0.477 0.228 AFRICA 246 G 0.039 0.069 0.074 - 0.122 0.060 EUROPE 380 A 0.289 0.358 0.411 - 0.189 0.121 EAST ASIA 286 G 0.002 0.003 0.003 - 0.003 0.002 AMERICA 181 G 0.213 0.282 0.335 - 0.013 0.006