What are the contraindications of orlistat? What are the side effects of orlistat? What should patient consider in their diet with orlistat? What causes diarrhea/constipation? Which drugs are used to decrease effects of constipation? What are the treatments for diarrhea? What is the prototype laxative? What are the indications for magnesium hydroxide? What is the mechanism for magnesium hydroxide? What are the contraindications for magnesiu, hydroxide?

1. What are the contraindications of orlistat?

malabsorption syndrome, prganic causes of obesity, cholestasis, use in caution with diabetes, thyroid disease, or anticoagulants

2. What are the side effects of orlistat?

may decrease A, D, K & E -- may require supplements

3. What should patient consider in their diet with orlistat?

should decrease intake of fate ,30% or risk of diarrhea/fecal incontinence -- should omit dose if meal contains no fat

4. What causes diarrhea/constipation?

an imbalance of water absorption in the intesitines -- too much water = diarrhea, too little water = constipation

5. Which drugs are used to decrease effects of constipation?

osmotic saline, milk of magnesia, bulk forming, stool softener, stimulants and lubricants

6. What are the treatments for diarrhea?

pull water out of the intestines, and focus on rehydrating the patient (dehyrdration can be lethal as a side effect of diarrhea)

7. What is the prototype laxative?

Milk of Magnesia (magnesium hydroxide)

8. What are the indications for magnesium hydroxide?

constipation, antacid, preoperative or diagnostic clearancce of the bowel

9. What is the mechanism for magnesium hydroxide?

pulls water into the intestines

10. What are the contraindications for magnesiu, hydroxide?

contraindicated for acute abdominal conditions (appendicitis) and caution in rnenal patients (ineffective excretion of magnesium causes toxicity)