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which osteoporosis medications have SC dosage forms? which osteoporosis medications have intranasal dosage forms? which osteoporosis medications have IM dosage forms? are falls a contraindication for warfarin therapy? amitriptyline could be changed to ______ in order to reduce fall risk, why? which OTC commonly used for sleep should be avoided in the elderly? PRN vs scheduled dosing? what are the 3 indications for considering calcitonin therapy in the elderly? what are the 3 "cons" for considering calcitonin therapy in the elderly? what are the 5 "cons" for considering bisphosphonate therapy in the elderly?  

Biology Sep 29, 2020
  1. which osteoporosis medications have SC dosage forms?
  2. which osteoporosis medications have intranasal dosage forms?
  3. which osteoporosis medications have IM dosage forms?
  4. are falls a contraindication for warfarin therapy?
  5. amitriptyline could be changed to ______ in order to reduce fall risk, why?
  6. which OTC commonly used for sleep should be avoided in the elderly?
  7. PRN vs scheduled dosing?
  8. what are the 3 indications for considering calcitonin therapy in the elderly?
  9. what are the 3 "cons" for considering calcitonin therapy in the elderly?
  10. what are the 5 "cons" for considering bisphosphonate therapy in the elderly?

 

Expert Solution

  1. which osteoporosis medications have SC dosage forms?

teriparatide, denosumab, salmon calcitonin

  1. which osteoporosis medications have intranasal dosage forms?

salmon calcitonin

  1. which osteoporosis medications have IM dosage forms?

salmon calcitonin

  1. are falls a contraindication for warfarin therapy?

NO! but physician should do a risk vs benefit comparison, and possibly just do ASA depending on conditions indicated...

  1. amitriptyline could be changed to ______ in order to reduce fall risk, why?

SSRI (data is better for falls, SSRI's are better for other reasons)

  1. which OTC commonly used for sleep should be avoided in the elderly?

diphenhydramine Tylenol PM

  1. PRN vs scheduled dosing?

scheduled dosing is much better and reduces risk of falls, more tolerance, more errors associated, etc.

  1. what are the 3 indications for considering calcitonin therapy in the elderly?

bone pain (metastasis);
2nd line for neuropathic conditions, postosteoporotic fracture pain;
great in those with OP

  1. what are the 3 "cons" for considering calcitonin therapy in the elderly?

nausea, calcium/phos abnormalities, complicated administration

  1. what are the 5 "cons" for considering bisphosphonate therapy in the elderly?

attention to renal function;
GI effects: must sit upright, nausea;
cost;
ONJ;
calcium abnormalities

 

 

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