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University of Illinois, Chicago NURS 531 Chapter 44: Anxiolytic and hypnotic drugs MULTIPLE CHOICE 1)Benzodiazepines enhance the effect of g-amino-butyric acid (GABA) on chloride ion channels by increasing the chloride conductance of each channel the frequency of channel opening the amount of time each channel remains open the affinity of chloride for the channel the recovery time of each channel 2
University of Illinois, Chicago
NURS 531
Chapter 44: Anxiolytic and hypnotic drugs
MULTIPLE CHOICE
1)Benzodiazepines enhance the effect of g-amino-butyric acid (GABA) on chloride ion channels by increasing
- the chloride conductance of each channel
- the frequency of channel opening
- the amount of time each channel remains open
- the affinity of chloride for the channel
- the recovery time of each channel
2. When used to induce sleep in persons with insomnia, benzodiazepines act to increase
- subjective ratings of sleep quality
- the proportion time spent in slow-wave sleep
- the amount of time taken to get to sleep
- the amount of rapid eye movement sleep
- the secretion of growth hormone during sleep
3. The attributes of zolpidem include
- a benzodiazepine structure
- being useful in treating anxiety
- an ultrashort duration of action
- a significant hangover effect
- a high risk of drug dependence
4. Flumazenil interacts with the g-amino-butyric acid (GABA) receptor so as to competitively inhibit the binding of
- only GABA
- only benzodiazepine drugs
- only b-carboline drugs
- both GABA and benzodiazepine drugs
- both benzodiazepine and b-carboline drugs
5. The use of buspirone in the treatment of anxiety disorders is characterized by
- a rapid onset of action
- a risk of drug dependence
- sedation and motor incoordination
- a lack of withdrawal effects
- blockade of 5-hydroxytryptamine 5-HT1A receptors
6. Midazolam is most commonly used as
- a hypnotic
- an anxiolytic
- an intravenous anesthetic
- an anticonvulsant
- a muscle relaxant
7. The short-acting benzodiazepines that are converted to inactive glucuronide metabolites include
- diazepam
- lorazepam
- chlordiazepoxide
- triazolam
- alprazolam
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