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Homework answers / question archive / University of Illinois, Chicago NURS 531 Chapter 22: The vascular system MULTIPLE CHOICE 1)Which vasoconstrictor substance is produced by vascular endothelial cells?   nitric oxide   bradykinin prostacyclin natriuretic peptide endothelin     2

University of Illinois, Chicago NURS 531 Chapter 22: The vascular system MULTIPLE CHOICE 1)Which vasoconstrictor substance is produced by vascular endothelial cells?   nitric oxide   bradykinin prostacyclin natriuretic peptide endothelin     2

Nursing

University of Illinois, Chicago

NURS 531

Chapter 22: The vascular system MULTIPLE CHOICE

1)Which vasoconstrictor substance is produced by vascular endothelial cells?

 

  1. nitric oxide

 

  1. bradykinin
  2. prostacyclin
  3. natriuretic peptide
  4. endothelin

 

 

2.    The opening of membrane potassium channels by minoxidil leads to

 

  1. increased potassium influx
  2. increased calcium influx
  3. inactivation of calcium channels
  4. membrane depolarization
  5. formation of cyclic GMP

 

 

3.    Both valsartan and enalapril

 

  1. increase serum potassium levels
  2. often cause a dry cough
  3. block angiotensin AT1 receptors
  4. inhibit formation of angiotensin II
  5. increase bradykinin levels

 

 

4.    Bosentan is an antagonist of

 

  1. endothelin ETA and ETB receptors
  2. angiotensin AT1 receptors
  3. angiotensin AT2 receptors
  4. nitric oxide receptors
  5. prostaglandin FP receptors

 

 

 

 

5.    In persons with heart failure, enalapril typically increases

 

  1. cardiac afterload
  2. cardiac preload
  3. vascular resistance
  4. cardiac output
  5. aldosterone secretion

6.    Which drug reduces sympathetic outflow from the central nervous system?

 

  1. fosinopril
  2. clonidine
  3. terazosin
  4. felodipine
  5. hydralazine

 

 

7.

Captopril is a structural analog of the terminal dipeptide of

1.

renin

2.

nitric oxide synthase

3.

endothelin

4.

angiotensin converting enzyme

5.

angiotensin I

 

 

8.

Effects similar to those of angiotensin converting enzyme inhibitors may be obtained in heart failure patients

 

by administering

1.

furosemide

2.

digoxin

3.

hydralazine and isosorbide dinitrate

4.

dobutamine

5.

nitroglycerin

 

 

9.

The adverse effects of terazosin and related drugs typically include

1.

hypokalemia

2.

drowsiness and dry mouth

3.

urinary retention in older men

4.

postural hypotension and edema

5.

bradycardia and syncope

 

 

10.

In persons with decompensated heart failure, nesiritide activates

1.

adrenergic alpha receptors

2.

adrenergic beta receptors

3.

adenylate cyclase

4.

guanylate cyclase

5.

myosin phosphatase

 

 

11.

The preferred drugs for the initial treatment of most patients with mild hypertension include

1.

hydralazine

2.

minoxidil

3.

hydrochlorothiazide

4.

methyldopa

5.

prazosin

 

 

12.

Fenoldopam is useful in treating hypertensive emergencies because of its ability to

1.

block adrenergic beta receptors

2.

block adrenergic alpha receptors

3.

block calcium channels

4.

open potassium channels

 

5.    activate dopamine D1 receptors

 

 

13.   Beginning therapy with low doses that are gradually increased over several months is appropriate when treating heart failure with

 

  1. digoxin
  2. furosemide
  3. dobutamine
  4. carvedilol
  5. nitroglycerin

14.   The progression of diabetic nephropathy may be slowed by

 

  1. propranolol
  2. enalapril
  3. hydrochlorothiazide
  4. amlodipine
  5. doxazosin

 

 

15.   The use of eplerenone in the treatment of heart failure is based on its ability to

 

  1. cause vasodilation
  2. inhibit sympathetic nervous system activity
  3. antagonize aldosterone
  4. inhibit angiotensin II formation
  5. increase cardiac contractile force

 

 

 

 

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