University of Illinois, Chicago

NURS 531

Chapter 22: The vascular system MULTIPLE CHOICE

1)Which vasoconstrictor substance is produced by vascular endothelial cells?

1. nitric oxide

2. bradykinin
3. prostacyclin
4. natriuretic peptide
5. endothelin

2.    The opening of membrane potassium channels by minoxidil leads to

1. increased potassium influx
2. increased calcium influx
3. inactivation of calcium channels
4. membrane depolarization
5. formation of cyclic GMP

3.    Both valsartan and enalapril

1. increase serum potassium levels
2. often cause a dry cough
3. block angiotensin AT1 receptors
4. inhibit formation of angiotensin II
5. increase bradykinin levels

4.    Bosentan is an antagonist of

1. endothelin ETA and ETB receptors
2. angiotensin AT1 receptors
3. angiotensin AT2 receptors
4. nitric oxide receptors
5. prostaglandin FP receptors

5.    In persons with heart failure, enalapril typically increases

1. cardiac afterload
2. cardiac preload
3. vascular resistance
4. cardiac output
5. aldosterone secretion

6.    Which drug reduces sympathetic outflow from the central nervous system?

1. fosinopril
2. clonidine
3. terazosin
4. felodipine
5. hydralazine