University of Houston MICRO 3332 Quiz 11 1)Which human ecosystem carries the greatest number of microbes? a

University of Houston

MICRO 3332

Quiz 11

1)Which human ecosystem carries the greatest number of microbes?

a.            Genitourinary tract

b.            Intestine

c.             Mouth d. Skin

e. Lungs

2.            Invading microbes usually need to overcome host defenses in which following order

a.            Physical barriers, cells of the innate immune system, adaptive immunity

b.            Physical barriers, adaptive immunity, cells of the innate immune system

c.             Adaptive immunity, cells of the innate immune system, physical barriers

d.            Adaptive immunity, physical barriers, cells of the innate immune system

3.            Which pair is mismatched

a.            Opsonization: can involve adaptive immune system

b.            Interferon Type 1: can make cell resistant to viral infection

c.             Macrophage: immune system cells that carry out phagocytosis

d.            Fever: induced by presence of pyrogens

e.            Alternative complement pathway: complement activated by antibodies; should be activated by contact between complement & pathogen via surface glycolipid complexes

4.            Which of the following kills cells infected with an intracellular pathogen such as a virus or bacterium

a.            Toll-like receptors

b.            Interferon type I

c.             Natural killer cells

d.            Cytotoxic T cells

e.            Two of the above are correct

5.            Which of the following happens during inflammation

a.            The capillaries supplying blood to the area become more leaky (i.e., permeable)

b.            Prostaglandins deaden nerve endings, alleviating pain

c.             Neutrophils release histamine

d.            All of the above

6.            Which of the following is true of the adaptive immune response

a.            B cells mostly mediate cellular immunity and T cells mostly mediate humoral immunity

b.            T cells can differentiate into antibody-secreting plasma cells

c.             A clonal population of plasma cells can produce antibodies to many different epitopes

d.            T cells can directly kill infected host cells but B cells cannot directly kill cells

e.            All are true

7.            These antibodies are primarily found in/on mucous membrane surfaces; they can act to prevent attachment of pathogens to these surfaces

a.            IgA

b.            IgD

c.             IgE

d.            IgG

e.            IgM

8.            Which cell type, molecule, or process listed below does not have a function or role in both the innate and adaptive immune systems?

a.            Macrophages

b.            Dendritic cells

c.             Complement

d.            Defensins

e.            Phagocytosis

9.            You’re infected with a pathogen; it is your first exposure to this pathogen. The first antibody types that will eventually appear in your blood to help fight this infection will be

a.            IgA

b.            IgD

c.             IgE

d.            IgG

e.            IgM

10.          Which of the following statements is not accurate regarding complement

a.            The effect of complement typically depends on activation of complement factor C3

b.            Complement are non-cellular protein factors

c.             Activated complement factors can combine to form pores in the plasma membrane of infecting cells and kill them

d.            Complement only works in conjunction with the adaptive immune system

e.            Complement is present in blood serum

11.          Which white blood cell type is not correctly matched with its proper function or feature

a.            Neutrophils: called polymorphonuclear leukocytes; can exit blood vessels and enter infected tissue

b.            Basophils: primary phagocytic cell type that fights infection

c.             Macrophages: important phagocytic cell type; can reside in certain tissues or wander around body

d.            Dendritic cells: works with adaptive immune system as an antigen presenting cell

e.            Monocyte: outside blood, differentiate into macrophages and dendritic cells