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Apart from suffering from recurrent and prolonged infections, Marie Curie also experienced the following signs and symptoms: fatigue, rapid heart rate, pale skin, easy bruising, prolonged bleeding from cuts, and dizziness
Apart from suffering from recurrent and prolonged infections, Marie Curie also experienced the following signs and symptoms: fatigue, rapid heart rate, pale skin, easy bruising, prolonged bleeding from cuts, and dizziness. Bone marrow transplant was not an option at that time and so blood transfusion was the treatment of choice.
1) Explain the reasoning behind these other signs and symptoms that Curie experienced?
2) Assume her blood group was A negative. Which blood groups can she receive? Which blood groups can she not receive? Explain in detail why?
3) Why is bone marrow transplant not an option?
Expert Solution
Answer:
1) These are the sogns and symptoms of aplastic anemia.Due to exposure to dangerous radioactive rays she suffered from the disorder aplastic anemia in which pancytopenia occurs that is decrease in all blood cell counts.
2) iF her blood group was A negative than she could receive blood from A- and O-
She cannot receive blood from AB and B group.
According to landsteiners law,her blood will have antibodies against B antigen,if this blood would have been transfused it will result into agglutination and clumping of RBCs will occur which is fatal and can cause death.
3)Bone marrow transplant is not an option because marie curie died 30 years before the discovery of bone marrow transplantion.
Also there was no history giving evidence of survival rates.
As first bone marrow transplantion was performed in 1956.
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