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1)Why is a knowledge of receptor subtypes important when developing a new pharmaceutical medication? 2)Describe the structural and functional differences between ionotropic and metabotropic receptors

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1)Why is a knowledge of receptor subtypes important when developing a new pharmaceutical medication?

2)Describe the structural and functional differences between ionotropic and metabotropic receptors.

3)Discuss the concept of allosteric receptor modulation. How is the influence of a positive or negative allosteric modulator different from the influence of a direct agonist or antagonist on a particular receptor’s functioning?