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what are vitamin D's 4 autocrine/paracrine actions? which agents for osteoporosis management are indicated for prevention only? which 3 agents for osteoporosis management are indicated for treatment only? which agents for osteoporosis management are indicated for both prevention and treatment? which bisphosphonate agents do not have any osteoporosis indications (YET)? what is the generic for Fosamax? class? what is the generic for Boniva? class? what is the generic for Actonel? class? what is the generic for Reclast? class? what is the generic for Forteo?

Biology Sep 29, 2020
  1. what are vitamin D's 4 autocrine/paracrine actions?
  2. which agents for osteoporosis management are indicated for prevention only?
  3. which 3 agents for osteoporosis management are indicated for treatment only?
  4. which agents for osteoporosis management are indicated for both prevention and treatment?
  5. which bisphosphonate agents do not have any osteoporosis indications (YET)?
  6. what is the generic for Fosamax? class?
  7. what is the generic for Boniva? class?
  8. what is the generic for Actonel? class?
  9. what is the generic for Reclast? class?
  10. what is the generic for Forteo?

Expert Solution

  1. what are vitamin D's 4 autocrine/paracrine actions?

inhibition of cell proliferation;
promotion of cell differentiation;
immune regulation;
effects on numerous genes

  1. which agents for osteoporosis management are indicated for prevention only?

conjugated estrogens

  1. which 3 agents for osteoporosis management are indicated for treatment only?

teriparatide (Forteo)
denosumab (Prolia)
salmon calcitonin (Miacalcin)

  1. which agents for osteoporosis management are indicated for both prevention and treatment?

all of the bisphosphonates: alendronate, ibandronate, risendronate, zoledronic acid
Raloxifene (Evista)

  1. which bisphosphonate agents do not have any osteoporosis indications (YET)?

etidronate (Didronel)
pamidronate (Aredia)
tiludronate (Skelid)

  1. what is the generic for Fosamax? class?

alendronate;
bisphosphonate

  1. what is the generic for Boniva? class?

ibandronate;
bisphosphonate

  1. what is the generic for Actonel? class?

risedronate;
bisphosphonate

  1. what is the generic for Reclast? class?

zoledronic acid;
bisphosphonate

  1. what is the generic for Forteo?

teriparatide

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