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Homework answers / question archive / PLEASE LIST THE RESOURCE FOR EACH QUESTION UNDER IT You may use your notes and book for this

PLEASE LIST THE RESOURCE FOR EACH QUESTION UNDER IT You may use your notes and book for this

Writing

PLEASE LIST THE RESOURCE FOR EACH QUESTION UNDER IT You may use your notes and book for this. Any other resources used, you must list. You are not allowed to search for online answer keys that may be posted. This assignment is meant to train you to be able to search for answers using credible resources. Please list your resources in APA format in the last question of this case history. If you used the CDC website, for example, be sure to offer a complete listing. Do not just list www.cdc.gov (Links to an external site.) (Links to an external site.) or just an index page if you used the subcategories within the index (the index was just the starting point or gateway). For APA: https://owl.purdue.edu/owl/research_and_citation/apa_style/apa_style_introduction.html (Links to an external site.) (Links to an external site.) Do not use the automatic citation generator. If you do it incorrectly (which most do), it will not format your source information correctly! (Q1) Scenario Tim is a 40-year-old sustainable farmer who works daily in his farm fields. After a long day getting his fields ready for planting, he comes in and falls into bed, exhausted. The next morning as he's taking a shower, he feels a small lump on the back of his leg, behind his knee. Since he can't really see it, he dries off and asks his wife to look at it. Initially she thinks it looks like a scab, but upon closer inspection she notices it has legs! She runs for the tweezers and pulls the tick off, and then notices that he actually has three more ticks embedded higher up on the back of his thigh. Signs and Symptoms Tim had been bitten by ticks and treated for Lyme disease before, so he decided to wait to see if a rash developed. After checking the spots daily for a week and not seeing anything other than a small, red, raised area around a few of the tick bite sites, he stopped worrying. About 10 days later, Tim developed a fever and started to have bouts of extreme fatigue that were not alleviated by resting or sleep. The fatigue got to the point that he couldn't get out of bed. When he started to act disoriented and confused, his wife drove him to the hospital. Testing Blood was drawn and sent to the hematology, clinical chemistry, and microbiology laboratories. What symptoms would indicate that Tim's disease could be due to an infection involving the central nervous system? (Q2) In the differential cell count, the hematology technologist who looked at Tim's blood noted a high proportion of "reactive" lymphocytes, and also saw abnormalities (see arrow) in several neutrophils. What is the significance of these findings in the peripheral blood smear? (Q3) While his attending physician struggled to figure out what was wrong, Tim became unresponsive. Additional samples were sent to serology to assess his exposure to viruses known to cause encephalitis, specifically West Nile Virus (WNV), Eastern Equine Encephalitis Virus (EEE), and Powassen Virus (POW), as well as tests for other tick-borne diseases common to his area. Serology Test Results: WNV, EEE, and POW—negative Lyme disease serology—equivocal Babesia microti and B. duncanii—negative Ehrlichia monocytogenes—negative Anaplasma phagocytophilium—positive Discuss the results of the collective laboratory tests— are the serology test results consistent with what the hematologist observed in the stained blood smear? (Q4) Do you think Tim has Lyme disease? (Q5) Diagnosis Tim was diagnosed with anaplasmosis, caused by Anaplasma phagocytophilium. Is it necessary for the hospital to report Tim's case of anaplasmosis to the CDC for disease surveillance? Why? (Q6) Over the next two months, seven other people with Tim's symptoms were admitted to the same regional hospital. Six tested positive for anaplasmosis and were successfully treated, but the seventh person died before a diagnosis could be reached. She subsequently was found to be positive for Anaplasma. In the previous year, there had been no cases of anaplasmosis diagnosed at the hospital. What epidemiological term(s) apply to this scenario? (what is the outbreak pattern?) (Q7) Treatment Once it was affirmed that Tim was infected with Anaplasma, treatment with IV ceftriaxone was immediately started via a peripherally inserted central catheter (PICC). After 2 days on the antibiotic he was alert but still overwhelmingly fatigued. After a week he was feeling well enough to be released from the hospital, but visited an infusion center daily for the rest of the month. He was also given oral doxycycline. By the end of the year, a total of 26 cases of anaplasmosis were diagnosed at the hospital, which was the only medical facility in Tim's county of residence. The county population (from census data) that year was 6,982 people. What is the incidence of anaplasmosis in Tim's county? (Q8) Is this also the prevalence of anaplasmosis in Tim's county? Why? (Q9) Additional Considerations Do you think that the reported incidence for anaplasmosis accurately reflects the burden of this disease for residents in the county? Why? (Q10) The incidence and prevalence of tick-borne borne diseases in general are increasing worldwide. What abiotic and biotic factors may be contributing to this increase? List of resources used. Please include your textbook/e-book with page numbers consulted, and lab manual if used. Reference class notes (if used) as name of lecturer, semester date, approximate title of lecture. There are no required number of sources, but do include ALL used. Not citing resources when used, is a violation of Academic Integrity standards in the Student Code of Conduct and may result in point deduction.

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