Homework answers / question archive / •Can Natural K cells target self-cells? Yes/No why How •Why phagocytic cells have developed two different methods to destroy the phagocytosed microbe? Give reasons •Why fever is considered a friend as well as as foe? Justify your answer with reasons •What is the difference between fever and hyperthermia (research question) Can complement deficiency lead to disease and how? Name at least on such disease

•Can Natural K cells target self-cells? Yes/No why How •Why phagocytic cells have developed two different methods to destroy the phagocytosed microbe? Give reasons •Why fever is considered a friend as well as as foe? Justify your answer with reasons •What is the difference between fever and hyperthermia (research question) Can complement deficiency lead to disease and how? Name at least on such disease

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•Can Natural K cells target self-cells? Yes/No why How

•Why phagocytic cells have developed two different methods to destroy the phagocytosed microbe? Give reasons

•Why fever is considered a friend as well as as foe? Justify your answer with reasons

•What is the difference between fever and hyperthermia (research question)

Can complement deficiency lead to disease and how? Name at least on such disease.

•Write down the role of each of the following

-C3a  C4a

-C3b  C4b

-C5a  C5a

-C5b  C2a

-C9     C9

Write down the advantages and disadvantages of inflammation

•What are function of following in inflammation

-Histamine

-ICAM

-Prostaglandin

-IL2

-TNF alpha

Are antibodies are the only immunoglobulins?

•Make a comparative table of isotype and allotype.

•How many constant domains are in

-IgG

-IgM

-Fc

-Fab

•Which type/s of antibodies provide primary protection against respiratory infection and how?

What is the difference between affinity and avidity? Write down the the significance of each.

•How can viral or bacterial antigen cause cross reactivity in humans? Give at least two examples

•Can viruses resist neutralization by antibodies? Yes/no? how?

•Answer the following with reference to ADCC and neutralization of viruses

a.  Which classes or isotypes of immunoglobulins are involved

b.  What is the role of the

                  Fab portion of the antibody

                    Fc portion of the antibody

•Why only IgD and IgM an act as BCR.

  •Write down the role of CD32.

Make sketches comparing activation of T-dependent and T-independent activation of B cells.

Explain differences in the two pathways with regards to:-

A) type of Antigen used

B)  Role of B cells

C) type of antibody response and whether immune memory occurs