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Homework answers / question archive / University of Illinois, Chicago NURS 531 Chapter 57: Harmful effects of drugs MULTIPLE CHOICE 1)The teratogenic effect of thalidomide usually causes   abnormal heart valves mental retardation testicular atrophy absence of long bones of limbs spina bifida     2

University of Illinois, Chicago NURS 531 Chapter 57: Harmful effects of drugs MULTIPLE CHOICE 1)The teratogenic effect of thalidomide usually causes   abnormal heart valves mental retardation testicular atrophy absence of long bones of limbs spina bifida     2

Nursing

University of Illinois, Chicago

NURS 531

Chapter 57: Harmful effects of drugs

MULTIPLE CHOICE

1)The teratogenic effect of thalidomide usually causes

 

  1. abnormal heart valves
  2. mental retardation
  3. testicular atrophy
  4. absence of long bones of limbs
  5. spina bifida

 

 

2.    Female offspring of women who received stilbestrol during pregnancy have an increased risk of

 

  1. lung cancer
  2. breast cancer
  3. vaginal cancer
  4. endometrial cancer
  5. heart valve defects

3.    The toxic metabolite of paracetamol, N-acetyl-p-benzoquinone imine, is believed to cause liver failure by

 

  1. inhibiting cytochrome P450 enzymes
  2. inhibiting lipid peroxidation
  3. depleting reactive oxygen species
  4. depleting reduced glutathione
  5. activating Ca2+ ATPases

4.    Which drug may elicit antibodies to the surface of red blood cells and thereby cause hemolytic anemia?

 

  1. methyldopa
  2. hydrochlorothiazide
  3. propranolol
  4. minoxidil
  5. clozapine

 

 

5.    Promoters are substances that increase the likelihood of cancer when administered

 

  1. alone
  2. before a co-carcinogen
  3. after a co-carcinogen
  4. before a primary carcinogen
  5. after a primary carcinogen

 

 

6.    Liver toxicity resulting from an overdose of paracetamol can be prevented by the administration of

 

  1. oxygen
  2. acetylcysteine
  3. folinic acid
  4. ethanol

 

  1. vitamin K

 

 

7.    Nephrotoxicity resulting from inhibition of prostaglandin synthesis is most likely to result from excessive administration of

 

  1. gentamicin
  2. captopril
  3. methicillin
  4. ibuprofen
  5. cyclosporin

 

 

8.    Exposure to mercury during pregnancy primarily causes abnormal development of the fetal

 

  1. brain
  2. bones
  3. face
  4. kidneys
  5. limbs

 

 

9.    Thrombocytopenia is the most common type II hypersensitivity reaction to

 

  1. chloramphenicol
  2. penicillin
  3. quinine
  4. sulfonamides
  5. methyldopa

 

 

 

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