Why Choose Us?
0% AI Guarantee
Human-written only.
24/7 Support
Anytime, anywhere.
Plagiarism Free
100% Original.
Expert Tutors
Masters & PhDs.
100% Confidential
Your privacy matters.
On-Time Delivery
Never miss a deadline.
University of Illinois, Chicago NURS 531 Chapter 42: Analgesic drugs MULTIPLE CHOICE 1)Opioids activate descending pathways that inhibit pain transmission by acting on neurons in the dorsal horn thalamus periaqueductal grey matter nucleus raphe magnus locus coeruleus 2
University of Illinois, Chicago
NURS 531
Chapter 42: Analgesic drugs
MULTIPLE CHOICE
1)Opioids activate descending pathways that inhibit pain transmission by acting on neurons in the
- dorsal horn
- thalamus
- periaqueductal grey matter
- nucleus raphe magnus
- locus coeruleus
|
2. |
The vanilloid receptor activated by capsaicin is a |
|
1. |
ligand-gated cation channel |
|
2. |
ligand-gated chloride ion channel |
|
3. |
ATP-sensitive potassium channel |
|
4. |
G-protein-coupled receptor |
|
5. |
protein kinase receptor |
|
|
|
|
3. |
The analgesic effect of morphine is mostly due to activation of |
|
1. |
delta opioid receptors |
|
2. |
kappa opioid receptors |
|
3. |
mu opioid receptors |
|
4. |
sigma opioid receptors |
|
5. |
tau receptors |
|
|
|
|
4. |
Stimulation of opioid receptors leads to |
|
1. |
increased guanylate cyclase activity |
|
2. |
decreased guanylate cyclase activity |
|
3. |
increased adenylate cyclase activity |
|
4. |
decreased adenylate cyclase activity |
|
5. |
closing of potassium channels |
|
|
|
|
5. |
Opioid drugs that exhibit partial agonist or mixed agonist-antagonist properties include |
|
1. |
naloxone and naltrexone |
|
2. |
methadone and meperidine |
|
3. |
fentanyl and sufentanil |
|
4. |
dynorphin and endorphin |
|
5. |
nalbuphine and pentazocine |
|
|
|
|
6. |
The best example of a partial agonist at mu opioid receptors is |
|
1. |
pentazocine |
|
2. |
buprenorphine |
|
3. |
cyclazocine |
|
4. |
nalbuphine |
|
5. |
codeine |
|
|
|
|
7. |
Which short-acting opioid agonist is administered as a transdermal skin patch? |
|
1. |
fentanyl |
|
2. |
methadone |
|
3. |
meperidine |
|
4. |
codeine |
|
5. |
propoxyphene |
8. Activation of kappa opioid receptors is primarily responsible for causing
- supraspinal analgesia
- euphoria
- dysphoria
- respiratory depression
- physical dependence
9. Which finding typically occurs in opioid poisoning but not in central nervous system depression due to other causes?
- coma
- hallucinations
- hypertension
- respiratory depression
- pinpoint pupils
10. The pharmacologic properties of morphine are
- well absorbed from the gut
- high oral bioavailability
- rapidly metabolized in neonates
- converted to active morphine-6-glucuronide
- excreted unchanged in the urine
11. Descending inhibition of dorsal horn pain transmission is mediated by neurons that release
- acetylcholine and dopamine
- enkephalins, 5-hydroxytryptamine, and noradrenaline
- glutamate and substance P
- bradykinin and prostanoids
- neuropeptides
12. Opioid drugs inhibit neurotransmitter release partly by
- opening potassium and calcium channels
- closing potassium and calcium channels
- opening potassium channels and closing calcium channels
- opening calcium channels and closing potassium channels
- depolarizing pre-synaptic neuronal membranes
13. Which transmitter is released at the first synapse in the dorsal horn ascending nociceptive pathway?
- glutamate
- enkephalin
- substance P
- g-amino-butyric acid
- noradrenaline
14. Actions of opioids that are not related to activation of mu, delta, or kappa opioid receptors include
- euphoria
- respiratory depression
- pupillary constriction
- constipation
- bronchospasm
Expert Solution
PFA
Archived Solution
You have full access to this solution. To save a copy with all formatting and attachments, use the button below.
For ready-to-submit work, please order a fresh solution below.
