1)

The anabolic effects of growth hormone are mediated primarily by

1.

somatotropin

2.

somatostatin

3.

somatomedin

4.

somatotrophin

5.

somatorelin

2.

During breast feeding, prolactin inhibits the release or response to

1.

oxytocin

2.

estradiol

3.

progesterone

4.

gonadotrophins

5.

hydrocortisone

3.

The effects of fludrocortisone can be antagonized by

1.

spironolactone

2.

beclomethasone

3.

metyrapone

4.

aldosterone

5.

aminoglutethimide

4.

Octreotide is correctly described as a

1.

short-acting analogue of somatotrophin

2.

long-acting analogue of somatotrophin

3.

short-acting analogue of somatostatin

4.

long-acting analogue of somatostatin

5.

long-acting analogue of somatomedin

5.

In the basic transactivation mechanism of glucocorticoid receptor control of gene expression, the ligand- bound glucocorticoid receptor dimer binds to

1.

nuclear factor kappa B sites

2.

regulatory sites of Fos/Jun transcription factors

3.

negative glucocorticoid response elements

4.

positive glucocorticoid response elements

5.

negative transcription factors

6.

Metyrapone inhibits the biosynthesis of

1.

only corticosterone

2.

only hydrocortisone

3.

only dehydroepiandrosterone

4.

both corticosterone and hydrocortisone

5.

corticosterone, hydrocortisone, and dehydroepiandrosterone

7.

Insulin-like growth factor-1 causes feedback inhibition of the secretion of

1.

prolactin

2.

melanocyte-stimulating hormone

3.

growth hormone

4.

corticotropin

5.

thyrotropin

8.

Polyuria may result from inhibition of antidiuretic hormone by

1.

desmopressin

2.

oxytocin

3.

carbamazepine

4.

ibuprofen

5.

lithium

9.

The adverse effects of high-dose or chronic administration of prednisone include

1.

muscle hypertrophy

2.

cataracts

3.

decreased abdominal fat

4.

thickened skin

5.

hypotension

10.

Cabergoline inhibits the anterior pituitary secretion of

1.

prolactin

2.

melanocyte-stimulating hormone

3.

thyrotropin

4.

somatotrophin

5.

corticotrophin

11.

The treatment of diabetes insipidus includes nasal administration of

1.

vasopressin

2.

desmopressin

3.

demeclocycline

4.

octreotide

5.

budesonide