University of Illinois, Chicago

NURS 531

Chapter 37: Chemical transmission and drug action in the central nervous system MULTIPLE CHOICE

1)Fast neurotransmitters in the central nervous system include

1. glutamate
2. dopamine
3. substance P
4. prostanoids
5. nerve growth factor

2.    Slow neurotransmitters and neuromodulators act mainly through

1. ligand-gated ion channels
2. G-protein-coupled receptors
3. enzymes
4. transcription factors
5. release of nitric oxide

3.    Drugs that are transported out of vascular endothelial cells in the central nervous system by P-glycoprotein include

1. most non-polar compounds
2. amino acid derivatives such as levodopa
3. highly ionized compounds
4. many anticancer and antibacterial drugs
5. most mood-altering drugs

4.    The relationship between the biochemical and cellular effects of a drug and its behavioral and therapeutic effects are best understood for drugs used in treating