University of Illinois, Chicago NURS 531 Chapter 15: 5-Hydroxytryptamine and the pharmacology of migraine MULTIPLE CHOICE 1)Urinary levels of 5-hydroxyindole acetic acid provide an indication of the body’s production of adenosine serotonin adenosine triphosphate histamine endothelin 2. Some of the effects of theophylline are attributed to antagonism of glutamate 5-hydroxytrypamine adenosine norepinephrine histamine 3. The effects of chemical mediators on platelets include stimulation of platelet aggregation by adenosine diphosphate stimulation of platelet aggregation by adenosine inhibition of platelet aggregation by adenosine diphosphate 4. inhibition of platelet aggregation by histamine 5. inhibition of platelet aggregation by serotonin 4. Cyproheptadine is useful in treating carcinoid syndrome because of its ability to 1. activate 5-HT1 receptors 2. block 5-HT1 receptors 3. activate 5-HT2 receptors 4. block 5-HT2 receptors 5. activate 5-HT4 receptors 5. In persons with irritable

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University of Illinois, Chicago NURS 531 Chapter 15: 5-Hydroxytryptamine and the pharmacology of migraine MULTIPLE CHOICE 1)Urinary levels of 5-hydroxyindole acetic acid provide an indication of the body’s production of adenosine serotonin adenosine triphosphate histamine endothelin 2

Nursing Jul 06, 2021

University of Illinois, Chicago

NURS 531

Chapter 15: 5-Hydroxytryptamine and the pharmacology of migraine MULTIPLE CHOICE

1)Urinary levels of 5-hydroxyindole acetic acid provide an indication of the body’s production of

adenosine
serotonin
adenosine triphosphate
histamine
endothelin

2. Some of the effects of theophylline are attributed to antagonism of

glutamate
5-hydroxytrypamine
adenosine
norepinephrine
histamine

3. The effects of chemical mediators on platelets include

stimulation of platelet aggregation by adenosine diphosphate
stimulation of platelet aggregation by adenosine
inhibition of platelet aggregation by adenosine diphosphate

4.	inhibition of platelet aggregation by histamine
5.	inhibition of platelet aggregation by serotonin

4.	Cyproheptadine is useful in treating carcinoid syndrome because of its ability to
1.	activate 5-HT1 receptors
2.	block 5-HT1 receptors
3.	activate 5-HT2 receptors
4.	block 5-HT2 receptors
5.	activate 5-HT4 receptors

5.	In persons with irritable bowel syndrome whose predominant symptom is constipation, intestinal peristaltic
	activity may be increased by drugs that
1.	activate 5-HT1 receptors
2.	block 5-HT1 receptors
3.	activate 5-HT2 receptors
4.	block 5-HT2 receptors
5.	activate 5-HT4 receptors

6.	Activation of 5-HT1D receptors is usually beneficial in persons suffering from
1.	carcinoid syndrome
2.	nausea and vomiting
3.	migraine headache
4.	constipation
5.	anxiety

7.	Retroperitoneal and mediastinal fibrosis is a characteristic adverse effect of
1.	methysergide
2.	ergotamine
3.	bromocriptine
4.	sumatriptan
5.	tegaserod

8.	Blockade of 5-HT3 receptors in vagal afferent neurons is useful in preventing
1.	migraine headache
2.	serotonin syndrome
3.	platelet aggregation
4.	nausea and vomiting
5.	constipation

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