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Homework answers / question archive / Annabeth and Percy are concerned about having a child with Niemann-Pick disease, which causes abnormal accumulation of fat in cells

Annabeth and Percy are concerned about having a child with Niemann-Pick disease, which causes abnormal accumulation of fat in cells

Biology

Annabeth and Percy are concerned about having a child with Niemann-Pick disease, which causes abnormal accumulation of fat in cells. This condition, which is very rare, has affected Annebeth's aunt (her father's sister) and Percy's grandmother (his father's mother). No one else in either family has the condition.

a) What is the most likely mode of inheritance of Niemann-Pick disease?

b) Based on their family history, what is the probability Annabeth and Percy's first child will be affected by Niemann-Pick disease?

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Answer:

A) The trait is autosomal recessive in nature because there are found skipping of generation. The trait is not specific to any sex.

b) 

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