Florida International University 16.1 Eukaryotic Epigenetic Gene Regulation 1)Why is eukaryotic gene expression more complex than prokaryotic gene expression? Where does eukaryotic gene expression regulation begin? What is the first level of organization in DNA? What are histones? What are nucleosome complexes and what is their function? What do the nucleosomes do if DNA encoding a specific gene is to be transcribed? When nucleosomes are spaced closely together, what occurs? When nucleosomes are spaced far apart, what occurs? What affects nucleosome spacing? How the histone proteins move is dependent on what? Describe the tag signals. What do the tags alter? When unmodified, histone proteins have what charge? How can the DNA molecule itself be modified? Describe the highly methylated (hypermethylated) DNA regions with deacetylated histones. Which changes are not permanent? What occurs if a gene is to be transcribed? If a gene is to remain turned off, what occurs?

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Florida International University 16

Biology May 03, 2021

Florida International University

16.1 Eukaryotic Epigenetic Gene Regulation

1)Why is eukaryotic gene expression more complex than prokaryotic gene expression?

Where does eukaryotic gene expression regulation begin?
What is the first level of organization in DNA?

What are histones?

What are nucleosome complexes and what is their function?
What do the nucleosomes do if DNA encoding a specific gene is to be transcribed?
When nucleosomes are spaced closely together, what occurs?
When nucleosomes are spaced far apart, what occurs?
What affects nucleosome spacing?
How the histone proteins move is dependent on what?
Describe the tag signals.
What do the tags alter?
When unmodified, histone proteins have what charge?
How can the DNA molecule itself be modified?
Describe the highly methylated (hypermethylated) DNA regions with deacetylated histones.
Which changes are not permanent?
What occurs if a gene is to be transcribed?
If a gene is to remain turned off, what occurs?

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