University of Minnesota, Morris - BIOLOGY 222 CH20 1)The key characteristic of a useful antimicrobial is selective toxicity

University of Minnesota, Morris - BIOLOGY 222

CH20

1)The key characteristic of a useful antimicrobial is selective toxicity.       

2.         Antimicrobials that have a high therapeutic index are less toxic to the patient.        

3.         Broad-spectrum antibiotics have minimal effect on the normal microbiota.

4.         Certain antimicrobials may be life-threatening.         

5.         Drugs that target peptidoglycan do not affect eukaryotes.                 

6.         Beta-lactam drugs are only effective against growing bacteria.        

7.         The MBC may be determined by an extension of the MIC.     

8.         Antimicrobial resistance can be due to spontaneous mutation or gene acquisition.              

9.         Viruses are very effectively treated with antibiotics.              

10.       Antifungal drugs usually target the cell membrane.