Biotechnology Lecture 6 Somatic= Animal biotechnology: Animal biotechnology: Promises of animal biotechnology and stem cells: Animal cloning: Cloning is copying

Biotechnology Lecture 6

• Somatic=
• Animal biotechnology:
• Animal biotechnology:
• Promises of animal biotechnology and stem cells:
• Animal cloning:
• Cloning is copying.
• Natural human clones: happens in 3/1000 births. Identical twins are genetically identical because they have identical genes in their nucleus, but they are not
• Barriers to cloning mammals:
• Overcoming the barriers:
• Embryo splitting:
• February 1997:
• Timeline of technologies in animal agriculture:
• You can take a white sheep and extract its DNA (nucleus). Then extract the egg from a black-faced sheep. You insert the white sheep DNA into the black-faced sheep egg to make an embryo, which is then planted into the surrogate mother.
• Ian Wilmut cloning steps:
• Quiescent cells:
• Morula:
• Why clone?
• Enviro-pig:
• First clone of an endangered animal:
• Genetically engineered pets:
• Why clone humans?
• Ethical considerations:
• Problems with cloning:
• Prometea:
• Cloning of donkey
• Cloning of dog
• Cloning of rhesus monkey
• Transgenic animal: an animal in which there has been a deliberate modification of its genome.
• Why transgenic animals?
• The uses of transgenic technology:
• 2007 Nobel prize in physiology or medicine:
• 1956/1968:
• 1970:
• 1973:
• 1978:
• 1988:
• 1998:
• hES=
• Why stem cells?
• Stem cells:
• Blastocyst:
• Sources of adult stem cells in humans:
• Autologous:
• Totipotent:
• Pluripotent:
• Multipotent:
• Unipotent:
• Tissue-specific stem cells:
• Types of adult stem cells:
• Induced pluripotent stem cells:
• Potency:
• Different attributes of stem cell types:
• Chimeras:
• 1999:
• Ethical issues with chimeric research:
• Ethics:
• Bioethics: