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Hemophilia A is an X-linked recessive disease caused by a lack of a coagulant called factor VIII (factor 8)

Biology Nov 19, 2020

Hemophilia A is an X-linked recessive disease caused by a lack of a coagulant called factor VIII (factor 8). This is caused by a mutation in a gene on the X chromosome called F8. Which of the following statements is correct?
1. If a carrier female and hemophiliac male have offspring, all of their sons will have hemophilia.
2. If a normal female (not carrier) and hemophiliac male have offspring, half of their daughters will have hemophilia.
3. If a hemophiliac female and unaffected male have offspring, all of their daughters will have hemophilia.
4. If a carrier female and unaffected male have offspring, half of their sons will have hemophilia.

- A. 1, 2 and 3
- B. 1 and 3
- C. 2 and 4
- D. 4 only
- E. All of 1, 2, 3 and 4 are correct.

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