1)   Allen B receives an IV dose of a corticosteroid (Solu- Medrol) for an acute exacerbation of asthma, but he does not begin to experience any clinical effects for several hours after the first dose

1)   Allen B receives an IV dose of a corticosteroid (Solu- Medrol) for an acute exacerbation of asthma, but he does not begin to experience any clinical effects for several hours after the first dose. The most likely explanation for the delay in the onset of the effect is that the corticosteroid ________________.


Causes the opening of ion channels in the cell membranes by binding membrane bound receptors.


Interacts with intracellular receptors to stimulate gene transcription and protein synthesis.


Interacts with receptors to activate G-proteins that convey signals to other proteins


Is poorly lipid soluble and distributes to its receptors very slowly