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1)Discuss the significance of an altered sleep– wake cycle in depression and bipolar disorder

Psychology

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1)Discuss the significance of an altered sleep– wake cycle in depression and bipolar disorder.

2)What are the three types of validity that ideally should be met by animal models of psychiatric disorders? Describe several models for bipolar disorder.

3)What is the monoamine hypothesis, and why has it been modified?

4)Provide evidence for the importance of 5-HT dysfunction in major depression.