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Pick any two diseases that require diagnostic tests to identify them from the body system

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Pick any two diseases that require diagnostic tests to identify them from the body system. Use one of the body systems: cardiovascular, respiratory, renal, hepatobiliary, lymphatic, reproductive or nervous systems. For each of the diseases, explain:

• Why is a particular test recommended?
• How does the test work?
• What information is obtained from the diagnostic test regarding the disease?
• Does the diagnosis need confirmation with another diagnostic test?