What two additional things can promote stomach acid? What are the different prototype antacids and what are there side effects? What are the effects of antacids? What is the prototype antacid? What is the mechanism of Sucralfate? Why is compliance a major issues of Sucraflate? What are the drug-drug interactions of Sucraflate? What is the physiological effect of Misoprostal? What are the adverse side effects of misprostal? what are the contraindications for misoprostol?

1. What two additional things can promote stomach acid?

(caused by bacterial infection by helicobacter pylori) and can be induced by NSAIDS such as aspirin (block postraglandin)

2. What are the different prototype antacids and what are there side effects?

Sodium based (systemic alkalosis in the blood), aluminum based (induces constipation), calcium based (hypercalcemia), magnesium based (induces diarrhea)

3. What are the effects of antacids?

Treat the excess acid and not the cause

4. What is the prototype antacid?

aluminum hydroxide mixed with Magnesium hydroxide (balancing diarrhea and constipation)

5. What is the mechanism of Sucralfate?

coats ulce, but compliance is a major problem, needs stomach acid to work

6. Why is compliance a major issues of Sucraflate?

because it needs to be taken on an empty stomach 3 hours after a meal but 1 hour before the next

7. What are the drug-drug interactions of Sucraflate?

avoid antacids and proton pump inhibitors

8. What is the physiological effect of Misoprostal?

Postraglandin analog that increases mucous secretion in the stomach, for NSAID induced acids

9. What are the adverse side effects of misprostal?

causes GI cramping

10. what are the contraindications for misoprostol?

contraindicated in pregnant women, and causes spontaneous abortions