Sample essay question: Describe the 1-compartment pharmacokinetic model describing plasma concentration vs time following an extra-vascular dose

Sample essay question: Describe the 1-compartment pharmacokinetic model describing plasma concentration vs time following an extra-vascular dose. Include reference to the following in your answer: i) ii) iii) The difference between the input to an intravenous bolus model and an extravascular model The difference between a 1- and 2-compartment model What is absolute bioavailability and what is the relevance of bioavailability to the extravascular model Note that the answer is not limited to the 3 points listed in the question, the question just states to include reference to these points in your answer. Don’t forget to answer the whole question!