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ex
- ex. epinephrine in heart cell causes increased heart rate, epinephrine in liver cell causes breakdown of liver glycogen
- signal pathways that act on proteins and structures that are already established and take seconds or less (ex. nerve cells, muscle cells, respiratory system)
- signal pathways that have to create new proteins and take hours or longer (ex. cell growth and development, digestion)
- long distance signaling used throughout the body, often hormones through blood stream
- signal molecule stays local and only affects targets in that area (ex. swelling, immune responses, tumor formation and growth, some fetal development)
- fast, specific pathways carried out by neurotransmitters
- cell signaling to a cell in contact, very localized, signal molecule is often membrane-bound (ex. fetal development)
- small hydrophobic molecules can only get to these (ex. Nitrogen Oxygen (NO) does this because it is so small)
- more common, takes larger signal molecules that can't fit through a membrane
- adding or removing a phosphate to turn on or off a signaling pathway inside the cell (ex. tyrosine kinases)
Expert Solution
- Same signal -> different response in different targets
ex. epinephrine in heart cell causes increased heart rate, epinephrine in liver cell causes breakdown of liver glycogen
- Fast Responses
signal pathways that act on proteins and structures that are already established and take seconds or less (ex. nerve cells, muscle cells, respiratory system)
- Slow Responses
signal pathways that have to create new proteins and take hours or longer (ex. cell growth and development, digestion)
- Endocrine signaling
long distance signaling used throughout the body, often hormones through blood stream
- Paracrine signaling
signal molecule stays local and only affects targets in that area (ex. swelling, immune responses, tumor formation and growth, some fetal development)
- Neuronal signaling
fast, specific pathways carried out by neurotransmitters
- Contact-dependent signaling
cell signaling to a cell in contact, very localized, signal molecule is often membrane-bound (ex. fetal development)
- Intracellular Receptors
small hydrophobic molecules can only get to these (ex. Nitrogen Oxygen (NO) does this because it is so small)
- Cell-surface Receptors
more common, takes larger signal molecules that can't fit through a membrane
- Signaling by protein phosphorylation
adding or removing a phosphate to turn on or off a signaling pathway inside the cell (ex. tyrosine kinases)
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