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University of Houston MICRO 3332 Quiz 12 1)Extracellular pathogens can attempt to avoid immune detection by a

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University of Houston

MICRO 3332

Quiz 12

1)Extracellular pathogens can attempt to avoid immune detection by

a.Inhibiting phagosome-lysosome fusion

b.            Growing within a phagolysosome

c.             Altering their cell-surface proteins

d.            All of the above

e.            None of the above

2.            The single greatest cause of gastroenteritis is

a.            Escherichia coli

b.            Salmonella enterica

c.             Rotavirus

d.            Shigella flexneri

3.            This group contains pathogens that can be differentiated by reactions observed on blood agar

a.            Staphylococcus

b.            Mycobacterium

c.             Streptococcus

d.            Giardia

e.            E. coli

4.            A certain pathogen is not easily acquired by individuals, but has an 85% mortality rate among those unfortunate enough to acquire it. This pathogen is

a.            Highly infectious and highly virulent

b.            Highly infectious and minimally virulent

c.             Minimally infectious and minimally virulent

d.            Minimally infectious and highly virulent

5.            What pathogen:description pair among A-E is incorrectly matched?

a.            Giardia: one of many bacterial types that cause gastroenteritis

b.            Staphylococcus aureus: some strains form exotoxins that cause gastroenteritis

c.             Mycobacterium tuberculosis: slow-growing, acid fast bacterium that causes a chronic respiratory disease

d.            Streptococcus pneumoniae: primary cause of pneumonia among humans

e.            Entamoeba: protozoan agent that causes severe dysentery

f.             A-E are all correctly matched

6.            Which of the following is a fomite?

a.            Water

b.            Droplets from a sneeze

c.             Pus

d.            Insects

e.            A hypodermic needle

7.            Botulism toxin, tetanus toxin, and vibrio enterotoxin are all examples of

a.            Endotoxins

b.            Exotoxins

 

c.             A-B type toxins

d.            Membrane-disrupting toxins

e.            Two of the above are correct

8.            The infectious dose data from this table tells you

 

a.            How much toxin it requires for each bacterium to cause disease

b.            How many experimental hosts are killed by each bacterium

c.             That Legionella is the most lethal pathogen listed

d.            That Treponema is the least infectious member of this group

e.            None of the above

9.            Which of the following virulence factors among A-D is correctly matched with its definition or characterization?

a.            Type III protein secretion: prevents opsonization of pathogen

b.            Phase variation: allows pathogen to switch between different forms of an extracellular antigen (e.g., flagellum)

c.             Protein A: a microbial factor that allows for attachment, typically a surface protein or surface glycoprotein

d.            Prevention of lysosome phagosome fusion: mechanism employed by an extracellular pathogen

e.            All are correctly matched

10.          Superantigen type toxins lead to the release of excessive amounts of     stimulating a hyperactive immune response that can lead to shock and death in the affected individual

a.            Antibodies

b.            Cytokines

c.             Water

d.            Antigen

e.            Interferon