University of Illinois, Chicago

NURS 531

Chapter 50: Basic principles of antimicrobial chemotherapy

MULTIPLE CHOICE

1)Which drug selectively inhibits bacterial RNA polymerase?

1. cytarabine
2. zidovudine
3. dactinomycin
4. rifampin
5. acyclovir

2.    Conjugation is an important mechanism for transfer of drug resistance genes between

1. coliform bacteria
2. staphylococci
3. enterococci
4. streptococci
5. spirochetes

3.    Cycloserine prevents the addition of terminal       residues to the peptide side chain on N- acetylmuramic acid

1. glycine
2. leucine
3. methionine
4. alanine
5. tyrosine

4.    Induction of bacterial proteins that enable energy-dependent efflux of drug molecules is an important mechanism of resistance to the

1. penicillins
2. aminoglycoside antibiotics
3. tetracycline antibiotics
4. macrolide antibiotics
5. folate reduction inhibitors

5.    Which drug is correctly paired with the type of organism in which it selectively inhibits dihydrofolate reductase?

1. trimethoprim-mammalian
2. pyrimethamine-mammalian
3. methotrexate-bacterial
4. methotrexate-protozoan
5. methotrexate-mammalian