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University of Illinois, Chicago NURS 531 Chapter 31: The control of blood glucose and drug treatment of diabetes mellitus MULTIPLE CHOICE 1)The characteristics of type 2 diabetes mellitus typically include insulin resistance absence of 1st and 2nd phase insulin secretion absence of 2nd phase insulin secretion only excessive insulin secretion impaired glucagon secretion 2
University of Illinois, Chicago
NURS 531
Chapter 31: The control of blood glucose and drug treatment of diabetes mellitus
MULTIPLE CHOICE
1)The characteristics of type 2 diabetes mellitus typically include
- insulin resistance
- absence of 1st and 2nd phase insulin secretion
- absence of 2nd phase insulin secretion only
- excessive insulin secretion
- impaired glucagon secretion
2. The actions of insulin include
- inhibition of glycogen synthesis
- inhibition of triglyceride synthesis
- inhibition of gluconeogenesis
- inhibition of protein synthesis
- inhibition of glucose uptake by muscle
3. Which drug binds to the peroxisome proliferator-activated receptor-gamma in adipose tissue, muscle, and liver?
- metformin
- pioglitazone
- repaglinide
- glipizide
- acarbose
4. The effects of metformin include
- increased appetite
- increased hepatic glucose output
- decreased hepatic glucose output
- hypoglycemia
- increased low-density lipoproteins
5. The mechanism of action of glipizide is
- stimulation of glucose transporters
- stimulation of insulin synthesis
- blockade of calcium channels
- activation of ATP-sensitive potassium channels
- blockade of ATP-sensitive potassium channels
6. Weight gain and fluid retention are most likely to occur in persons receiving
- metformin
- insulin lispro
- nateglinide
- pioglitazone
- acarbose
7. The characteristics of insulin glargine include:
- rapidly and completely absorbed after injection
- provides a constant basal insulin supply
- has an intermediate duration of action
- used in treating diabetic ketoacidosis
- contains a lysine-proline amino acid transposition
8. The most common adverse effect of glipizide is
- hypoglycemia
- weight loss
- fluid retention
- liver dysfunction
- lactic acidosis
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