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New Mexico State University BIO 226 PhysioEx Lab Report Exercise 4: Endocrine System Physiology Activity 4: Measuring Cortisol and Adrenocorticotropic Hormone Date: 1 September 2019 Pre-lab Quiz Results 1)Cortisol____________ ACTH___________ CRH__________ Cushing's syndrome refers to___________ A condition of hypocortisolism_____________ Experiment Results Predict Questions Stop & Think Questions Normally high levels of cortisol would inhibit release of Which hormone(s) stimulate(s) the pituitary gland to release ACTH? Experiment Data Patient Cortisol (mcg/dl) High or low ACTH (pg/ml) High or low 1 3
New Mexico State University
BIO 226
PhysioEx Lab Report
Exercise 4: Endocrine System Physiology
Activity 4: Measuring Cortisol and Adrenocorticotropic Hormone
Date: 1 September 2019
Pre-lab Quiz Results
1)Cortisol____________
- ACTH___________
- CRH__________
- Cushing's syndrome refers to___________
- A condition of hypocortisolism_____________
Experiment Results
Predict Questions
Stop & Think Questions
- Normally high levels of cortisol would inhibit release of
- Which hormone(s) stimulate(s) the pituitary gland to release ACTH?
Experiment Data
|
Patient |
Cortisol (mcg/dl) |
High or low |
ACTH (pg/ml) |
High or low |
|
1 |
3.83 |
Low |
18.23 |
Low |
|
2 |
33.21 |
High |
14.48 |
Low |
|
3 |
43.64 |
High |
85.93 |
High |
|
4 |
2.84 |
Low |
103.87 |
High |
|
5 |
54.61 |
High |
19.70 |
Low |
Table 4.1 Cortisol and ACTH Disorders
|
|
Cortisol Level |
ACTH Level |
|
Cushing's syndrome (primary hypercortisolism) |
High |
Low |
|
latrogenic Cushing's syndrome |
High |
Low |
|
Cushing's disease (secondary hypercortisolism) |
High |
High |
|
Addision's disease (primary adrenal insu?ciency) |
Low |
High |
|
Secondary adrenal insu?ciency (hypopituitarism) |
Low |
Low |
Post-lab Quiz Results
You scored 100% by answering 6 out of 6 questions correctly.
- Under normal conditions, if the amount of secreted CRH increases, then
- Under normal conditions, if the amount of secreted ACTH increases, then
- Under normal conditions, if the amount of secreted cortisol increases, then
- If a hypersecreting pituitary tumor develops, then an expected outcome is
- If a hypersecreting adrenal cortex tumor develops, then an expected outcome is
- A patient's chart lists the diagnosis of Addison's disease. Therefore, you expect
Review Sheet Results
- Which patient would most likely be diagnosed with Cushing's disease (view Table 4.1 in Experiment Results)? Why?
- Which two patients have hormone levels characteristic of Cushing's syndrome (view Table
4.1 in Experiment Results)?
- Patient 2 is being treated for rheumatoid arthritis with prednisone. How does this information change the diagnosis (view Table 4.1 in Experiment Results)?
- Which patient would most likely be diagnosed with Addison's disease (view Table 4.1 in Experiment Results)? Why?
Expert Solution
PFA
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