Homework 3 – Multi-locus Selection, Mutation and Gene Flow 1)The forward and reverse mutation rates at a certain locus in E

Homework 3 – Multi-locus Selection, Mutation and Gene Flow

1)The forward and reverse mutation rates at a certain locus in E. coli are

A to a               5 x 10^-5

a to A               3 x 10^-3

2. Consider the contribution of the following gene to running speed in Alaskan huskies.  We examine the following population of huskies and find:

Genotype                      Average Speed                       Relative Frequency

A₁A₁                                          6.0 m/s                                                0.15

A₁A₂                                          9.0 m/s                                                0.36

A₂A₂                                       12.0 m/s                                                 0.49

ANS:

3. A mainland population of 1000 blue iguanas have the neutral alleles A1 and A2 with frequencies of A1 = 0.50 and A2 = 0.50. A new population of blue iguanas is founded on Lizard Island with a population size of 10 males and 15 females.  The neutral alleles A1 and A2 are present in the population with frequencies of A1 = 0.30 and A2 = 0.70.

Migrants begin moving from the mainland to Lizard Island at a rate of 1 migrant per generation.

1. 1. Calculate the change in frequency (?p) of the A1 allele after one generation of migration.

1. 2. What will the new frequency (p?) of A1 be in the island population after one generation of migration ?

4. In the paper by Lailvaux et al. 2014, “Trait compensation and sex-specific aging of performance in male and female professional basketball players,” based upon the results shown in Figure 2, which sex shows a potential trade-off in performance allocation between the three scoring types?  Compensation between scoring types involves which types of shooting?  How does aging change the strength and direction of natural selection over an athlete’s lifetime?  What’s the fitness payoff for a professional athlete (Hint: it is not survive longer and make more babies!  Think of LeBron James)?