1)Describe the signaling mechanisms of the 5-HT1A and 5-HT2A receptor subtypes

1)Describe the signaling mechanisms of the 5-HT1A and 5-HT2A receptor subtypes.

2)List the drugs mentioned in the text that act on 5-HT1A, 5-HT1B/1D, 5-HT2A, and 5-HT3 receptors, and describe the behavioral effects of each drug in rodents or humans.

3)Some of the important functions mediated by brain 5-HT have been studied using Tph2-knockout mice along with mice that have developed without central serotonergic neurons. Discuss the various ways in which these mice differ from normal mice behaviorally and physiologically.