1)The text states, “Glutamate is the workhorse transmitter for fast excitatory signaling in the nervous system

1)The text states, “Glutamate is the workhorse transmitter for fast excitatory signaling in the nervous system.” What is the evidence for this statement?

2)Describe the three subtypes of ionotropic glutamate receptors, including how they were named, their subunit structure, and their ion conductances.

3)Describe the properties of the NMDA receptor, including its binding sites both outside of and within the ion channel. What conditions are necessary for the receptor channel to open, and how are these conditions related to the idea that the NMDA receptor is a “coincidence detector”?