What is true of the rate of cancer in post cancer treatment patients? What are the classes of antimetabolite anticancer agents? and what do they target? How do antifolates function? How do nucleosides function and what is the prototype? What is the target of bloth cell cycle dependent and indpendent drugs? What is the general makeup of DNA? What part of DNA do antimetabolites mimic? What is the difference between RNA and DNA? What is the target of antibiotics? When do alkylating agents bind to DNA? What is a 5-Fluorouracil?

1. What is true of the rate of cancer in post cancer treatment patients?

Anti-cancer treatments can often cause other cancers later on due to effecting the DNA

2. What are the classes of antimetabolite anticancer agents? and what do they target?

Antimetabolites target the S-phase (DNA synthesis) and are cycle specific -- antifolates and nucelosides

3. How do antifolates function?

block folate from incorporating into DNA

4. How do nucleosides function and what is the prototype?

interfere with the synthesizing of new DNA -- 5-fluorouracil

5. What is the target of bloth cell cycle dependent and indpendent drugs?

DNA

6. What is the general makeup of DNA? What part of DNA do antimetabolites mimic?

deoxyribose (sugar back bone) and A, G, T, C -- ribonucleic base pairs -- they are similar to these components needed for DNA synthesis

7. What is the difference between RNA and DNA?

RNA -- ribonucleic backbone acid and instead of T's you have U's

8. What is the target of antibiotics?

antibiotics disrupt DNA function

9. When do alkylating agents bind to DNA?

in both cycling and non cycling cells

10. What is a 5-Fluorouracil?

5-FU -- anti-metabolite is most effective against tymors with high growth rate and works as a false metabolite to prevent DNA synthesis