What are the different administration routes of insulin? What is true of the IV delivery of regular insulin? What are the complications of insulin therapy? What are the symptoms of hypoglycemia? What are the significant classes of drugs that interact with insulin? What are the effects of combining glucocorticoids and insulin? What is the effect of alcohol and insulin? What are the effects of beta blockers and insulin? What are the effects of oral antidiabetics and insulin? What is the goal of insulin dosing?

1. What are the different administration routes of insulin?

Injected (jet injectors, insulin pens), insulin pumom IV regular insulun, inhaled, sublingual, trandsdermal, transplantation of pancreatic B cells

2. What is true of the IV delivery of regular insulin?

only insulin that can be given for emergency treatment of ketoacidsos, and usually mixed with slower acting forms of insulun

3. What are the complications of insulin therapy?

hypoglycemia, lipodystrophies and allergic reactions

4. What are the symptoms of hypoglycemia?

increased anxiety, confusion, blurred vision, cold sweating, dizziness, headache, increased pulse rate

5. What are the significant classes of drugs that interact with insulin?

glucocorticoids, alcohol, beta blockers and oral antidiabetic drugs

6. What are the effects of combining glucocorticoids and insulin?

glucocorticoids can increase blood glusoe

7. What is the effect of alcohol and insulin?

alcohol may increase the hypoglycemic effect of insulin

8. What are the effects of beta blockers and insulin?

may mask symptoms of and prolong hypoglycemia

9. What are the effects of oral antidiabetics and insulin?

generally not advocated due to hypglycemic risks, but is done for type 2 diabetics

10. What is the goal of insulin dosing?

to keep blood glucose levels in a normal range; above 60mg/ml and below 200 mg/ml or less than 8% HbA1c