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Scientific advantages of the Modification of Somatic cells through the new technology CRISPER/Cas9 gene editing tool

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Scientific advantages of the Modification of Somatic cells through the new technology CRISPER/Cas9 gene editing tool.

•             What are the strengths and weaknesses of this technology

•             250-300 words

•             AMA citation

Must include a minimum of 3 primary scientific articles or other high-quality sources.

I support using CRISPR-Cas9 technology because it makes it possible to introduce, delete, or modify genetic material in specific locations throughout the genome, which is beneficial in reducing the occurrence of diseases and other medical conditions . When it comes to editing the genome, CRISPR-Cas9 offers the capacity to edit several genes simultaneously, making the technology more straightforward, more effective, and more amenable to scaling up.   According to Chang et al., rapid application development of various therapeutic methods is possible because of the automation of the CRISPR-Cas9 system, which ultimately results in shorter development cycles compared to other genome editing techniques. Therefore, I support CRISPR-Cas9 use because it is straightforward and effective.  Chang et al. affirm that the bioinformatics methods used to determine the sequences best suited for creating guide RNA have been improved. In addition, it can optimize the experimental circumstances, which permits the development of robust processes that guarantee the utilization of the intended mutation.

 The use of the CRISPR/Cas9 technology carries some inherent dangers because it has the potential to cause alterations that are not intended, some of which may be harmful. Concerns regarding CRISPR/Cas9 vary from ethical issues to a lack of basic knowledge regarding the difficulties associated with gene alteration. The primary reason is that once the method alters an organism's genes and introduces them to another organism, it cannot revert to its original state. This may sound scary to people who aren’t much aware of this technology and that is why informed consent is crucial. Modification of Somatic cells through informed consent should be allowed.

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