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Many of the intermediates that form during de novo purine biosynthesis are highly reactive

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Many of the intermediates that form during de novo purine biosynthesis are highly reactive. It has recently been shown that the enzymes that makeup the de novo purine biosynthesis pathway co-localize in the cytosol in dynamic membrane-less organelles that are known as purinosomes.

For this discussion I want you to discuss why it would be advantageous for metabolic enzymes to co-localize in membrane-less organelles and suggest what other pathways might behave in a similar way.

This is the question that I need help answering, the response should be at least a paragraph long and any references that you use copy and paste the link at the end of the paper.