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Myotonic dystrophy is an autosomal recessive disorder affecting 1 in 500 people in Quebec

Sociology

Myotonic dystrophy is an autosomal recessive disorder affecting 1 in 500 people in Quebec.

a. What is the expected frequency for the dominant allele in the Quebec population?

b.What is the expected frequency for the recessive allele in the Quebec population?

c.What percent of the Quebec population would you expect to be homozygous for the normal (non-disease) allele?

d. Myotonic dystrophy affects one in 7500 people in all of Canada. What would be the expected frequency of carriers of myotonic dystrophy in Canada?

e.Assuming the population of Canada is 30 million people, what number of people in Canada would you expect to be carriers?

 

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